Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2ea2F77Methionine aminopeptidase 2

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2ea2F77Methionine aminopeptidase 2/1.000
1yw8A75Methionine aminopeptidase 2/0.687
1yw9A84Methionine aminopeptidase 2/0.680
2ea4F79Methionine aminopeptidase 2/0.622
1r58AO5Methionine aminopeptidase 2/0.601
1yw7A41Methionine aminopeptidase 2/0.562
1r5gAO1Methionine aminopeptidase 2/0.552
2oazI96Methionine aminopeptidase 2/0.543
2ga2A19Methionine aminopeptidase 2/0.530
1qzyTDEMethionine aminopeptidase 2/0.523
1r5hAO2Methionine aminopeptidase 2/0.509
3aezGDPPantothenate kinase2.7.1.330.479
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.456
3opxU5PSuppressor of disruption of TFIIS/0.449
2wvlGDDMannosyl-3-phosphogylcerate synthase/0.444
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3h3t16HCollagen type IV alpha-3-binding protein/0.443
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
1obnASVIsopenicillin N synthase1.21.3.10.440
4gd40WSLysine-specific demethylase 4A1.14.110.440