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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2c68CT6Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2c68CT6Cyclin-dependent kinase 22.7.11.221.000
1w8cN69Cyclin-dependent kinase 22.7.11.220.657
4fklCK2Cyclin-dependent kinase 22.7.11.220.558
2c6o4SPCyclin-dependent kinase 22.7.11.220.543
3rahO1ZCyclin-dependent kinase 22.7.11.220.541
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.522
3r71X86Cyclin-dependent kinase 22.7.11.220.520
2a0cCK9Cyclin-dependent kinase 22.7.11.220.517
3r8vZ62Cyclin-dependent kinase 22.7.11.220.514
3r8pZ46Cyclin-dependent kinase 22.7.11.220.509
4kd11QKCyclin-dependent kinase 22.7.11.220.505
2exmZIPCyclin-dependent kinase 22.7.11.220.504
3r7yZ04Cyclin-dependent kinase 22.7.11.220.499
3qqlX03Cyclin-dependent kinase 22.7.11.220.497
3qwjX6ACyclin-dependent kinase 22.7.11.220.496
3rm618ZCyclin-dependent kinase 22.7.11.220.494
3r83Z14Cyclin-dependent kinase 22.7.11.220.492
3lfqA28Cyclin-dependent kinase 22.7.11.220.489
1b38ATPCyclin-dependent kinase 22.7.11.220.488
4ek816KCyclin-dependent kinase 22.7.11.220.482
3r8uZ31Cyclin-dependent kinase 22.7.11.220.480
2btsU32Cyclin-dependent kinase 22.7.11.220.479
3r9nZ68Cyclin-dependent kinase 22.7.11.220.478
3rpo24ZCyclin-dependent kinase 22.7.11.220.478
3lfnA27Cyclin-dependent kinase 22.7.11.220.475
5aniES4Cyclin-dependent kinase 22.7.11.220.475
1e1xNW1Cyclin-dependent kinase 22.7.11.220.473
3qzgX67Cyclin-dependent kinase 22.7.11.220.473
2r3fSC8Cyclin-dependent kinase 22.7.11.220.472
2r3gSC9Cyclin-dependent kinase 22.7.11.220.472
2a4lRRCCyclin-dependent kinase 22.7.11.220.471
1y8yCT7Cyclin-dependent kinase 22.7.11.220.468
3pj8404Cyclin-dependent kinase 22.7.11.220.465
4fkj11KCyclin-dependent kinase 22.7.11.220.465
1oirHDYCyclin-dependent kinase 22.7.11.220.464
3iggEFQCyclin-dependent kinase 22.7.11.220.464
2vtsLZCCyclin-dependent kinase 22.7.11.220.463
2c6kDT2Cyclin-dependent kinase 22.7.11.220.461
3r7uX96Cyclin-dependent kinase 22.7.11.220.458
1ykr628Cyclin-dependent kinase 22.7.11.220.456
3r1yX76Cyclin-dependent kinase 22.7.11.220.456
3lfsA07Cyclin-dependent kinase 22.7.11.220.455
3qx2X63Cyclin-dependent kinase 22.7.11.220.451
2r3kSCQCyclin-dependent kinase 22.7.11.220.450
3r8lZ30Cyclin-dependent kinase 22.7.11.220.450
3qu0X40Cyclin-dependent kinase 22.7.11.220.449
1pxjCK2Cyclin-dependent kinase 22.7.11.220.447
1aq1STUCyclin-dependent kinase 22.7.11.220.446
1pxlCK4Cyclin-dependent kinase 22.7.11.220.446
3rk909ZCyclin-dependent kinase 22.7.11.220.446
4fkg4CKCyclin-dependent kinase 22.7.11.220.446
1oitHDTCyclin-dependent kinase 22.7.11.220.445
2c69CT8Cyclin-dependent kinase 22.7.11.220.445
3rjc06ZCyclin-dependent kinase 22.7.11.220.445
1h0w207Cyclin-dependent kinase 22.7.11.220.443
1v1k3FPCyclin-dependent kinase 22.7.11.220.443
1oiyN41Cyclin-dependent kinase 22.7.11.220.442
3rk708ZCyclin-dependent kinase 22.7.11.220.442
3qtrX36Cyclin-dependent kinase 22.7.11.220.441
4fkv61KCyclin-dependent kinase 22.7.11.220.441
1gz8MBPCyclin-dependent kinase 22.7.11.220.440
2w06FRVCyclin-dependent kinase 22.7.11.220.440
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.440