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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.608
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.597
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.593
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.579
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.573
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.558
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.553
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.544
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.542
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.533
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.532
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.531
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.529
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.519
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.517
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.515
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.511
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.489
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.488
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.487
2vnwM01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.484
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.483
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
4xw4ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.465
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.465
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
4yxsEMUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
1jbpADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443