sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1vzq | SHY | Prothrombin | 3.4.21.5 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 1.000 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.732 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.694 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.674 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.664 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.649 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.646 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.643 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.640 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.640 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.636 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.636 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.631 | |
| 2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.631 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.630 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.629 | |
| 1k21 | IGN | Prothrombin | 3.4.21.5 | 0.627 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.627 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.624 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.621 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.620 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.619 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.618 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.610 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.607 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.606 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.606 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.605 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.604 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.601 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.599 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.597 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.595 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.595 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.593 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.593 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.593 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.592 | |
| 4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.592 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.592 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.590 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.586 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.581 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.580 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.580 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.579 | |
| 3dux | 64U | Prothrombin | 3.4.21.5 | 0.579 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.578 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.578 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.578 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.577 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.576 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.573 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.572 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.572 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.570 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.569 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.566 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.565 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.565 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.564 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.563 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.560 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.560 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.560 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.559 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.558 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.558 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.558 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.557 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.557 | |
| 4ban | M6S | Prothrombin | 3.4.21.5 | 0.557 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.556 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.556 | |
| 4baq | M4Z | Prothrombin | 3.4.21.5 | 0.555 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.554 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.550 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.548 | |
| 4ayv | 9MQ | Prothrombin | 3.4.21.5 | 0.547 | |
| 1riw | OSC | Prothrombin | 3.4.21.5 | 0.545 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.544 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.543 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.540 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.539 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.538 | |
| 2bxt | C2D | Prothrombin | 3.4.21.5 | 0.536 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.535 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.531 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.530 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.529 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.527 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.527 | |
| 3utu | 1TS | Prothrombin | 3.4.21.5 | 0.516 | |
| 1c1u | BAI | Prothrombin | 3.4.21.5 | 0.514 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.511 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.509 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.504 | |
| 3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.496 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.494 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.494 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.489 | |
| 1uvs | I11 | Prothrombin | 3.4.21.5 | 0.485 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.475 | |
| 3biv | 11U | Prothrombin | 3.4.21.5 | 0.465 | |
| 3ihz | FK5 | Peptidylprolyl isomerase | / | 0.463 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.458 | |
| 1c5n | ESI | Prothrombin | 3.4.21.5 | 0.454 | |
| 2p2x | SAH | Diphthine synthase | / | 0.452 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.448 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.446 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.445 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.445 | |
| 3c1o | NAP | Eugenol synthase | / | 0.443 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.442 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.440 |