sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1vhn | FMN | tRNA-dihydrouridine synthase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1vhn | FMN | tRNA-dihydrouridine synthase | / | 1.000 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.522 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.473 | |
| 4bf9 | FMN | tRNA-dihydrouridine(16) synthase | / | 0.471 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.463 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.461 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.448 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.446 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.446 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.445 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.443 | |
| 3gr8 | FMN | NADPH dehydrogenase | / | 0.443 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.443 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 3b05 | IPE | Isopentenyl-diphosphate delta-isomerase | / | 0.442 | |
| 3lcj | COA | Phosphopantetheine adenylyltransferase | / | 0.441 | |
| 3rba | COD | Phosphopantetheine adenylyltransferase | / | 0.441 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.440 |