Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1u26IHSMyo-inositol hexaphosphate phosphohydrolase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1u26IHSMyo-inositol hexaphosphate phosphohydrolase/1.000
3rucNADUDP-N-acetylglucosamine 4-epimerase/0.463
2rhrEMOPutative ketoacyl reductase1.3.10.454
4du82P0Mevalonate diphosphate decarboxylase/0.454
4l4xNDPAmphI/0.454
3h86AP5Adenylate kinase/0.453
1h6cNDPGlucose--fructose oxidoreductase1.1.99.280.452
2uuvFADAlkyldihydroxyacetonephosphate synthase2.5.1.260.450
1hw8ADP3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.449
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.448
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.447
2wo7ASVIsopenicillin N synthase1.21.3.10.447
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.447
4q71FADBifunctional protein PutA/0.447
1jpaANPEphrin type-B receptor 22.7.10.10.446
3bxsDRSGag-Pol polyprotein3.4.23.160.446
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.446
3tqhNDPQuinone oxidoreductase/0.445
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.444
3gnqNADGlyceraldehyde-3-phosphate dehydrogenase/0.444
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.444
3t2vKKJPeptidoglycan recognition protein 1/0.443
1rm3NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.440