sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1u0h | FOK | Adenylate cyclase type 2 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1u0h | FOK | Adenylate cyclase type 2 | / | 1.000 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 1.000 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.712 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.712 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.697 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.697 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.646 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.646 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.638 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.638 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.637 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.637 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.628 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.628 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.628 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.628 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.605 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.605 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.580 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.580 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.574 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.574 | |
| 3c16 | FOK | Adenylate cyclase type 2 | / | 0.566 | |
| 3c16 | FOK | Adenylate cyclase type 5 | / | 0.566 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.541 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.541 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.450 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.449 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.448 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.445 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.445 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.444 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.442 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.442 |