sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 1.000 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.684 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.670 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.659 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.512 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.499 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.499 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.495 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.495 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.494 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.491 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.491 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.491 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.491 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.486 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.486 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.486 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.486 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.485 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.485 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.483 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.482 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.482 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.482 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.480 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.478 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.472 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.471 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.471 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.469 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.469 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.467 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.466 | |
| 3wec | AUI | Cytochrome P450 | / | 0.466 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.461 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.459 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.457 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.456 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.452 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.449 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.449 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.448 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.448 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4egn | TWO | Cytochrome P450 | / | 0.447 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.446 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.446 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4ict | 1ED | Mycocyclosin synthase | 1.14.21.9 | 0.445 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.445 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.444 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.443 |