sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1lon | IMO | Adenylosuccinate synthetase isozyme 1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1lon | IMO | Adenylosuccinate synthetase isozyme 1 | / | 1.000 | |
| 2dgn | DOI | Adenylosuccinate synthetase isozyme 1 | / | 0.611 | |
| 1ksz | PGS | Adenylosuccinate synthetase | / | 0.580 | |
| 1cg3 | IMO | Adenylosuccinate synthetase | / | 0.578 | |
| 1qf5 | RPL | Adenylosuccinate synthetase | / | 0.576 | |
| 2gcq | DOI | Adenylosuccinate synthetase | / | 0.573 | |
| 1p9b | IMO | Adenylosuccinate synthetase | / | 0.568 | |
| 1qf4 | RPD | Adenylosuccinate synthetase | / | 0.558 | |
| 1cg4 | IMO | Adenylosuccinate synthetase | / | 0.550 | |
| 1cg1 | IMO | Adenylosuccinate synthetase | / | 0.533 | |
| 1nht | PGS | Adenylosuccinate synthetase | / | 0.527 | |
| 1cg0 | IMO | Adenylosuccinate synthetase | / | 0.522 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.469 | |
| 5dp2 | NAP | CurF | / | 0.461 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.458 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.450 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.449 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.448 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.445 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.445 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.445 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.444 | |
| 4nu5 | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.444 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.443 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.442 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.442 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.442 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.441 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.440 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.440 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.440 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.440 |