Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1jtqLY3Thymidylate synthase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1jtqLY3Thymidylate synthase/1.000
1dnaCB3Thymidylate synthase/0.692
1axwMTXThymidylate synthase/0.668
1fwmCB3Thymidylate synthase/0.617
1nceCB3Thymidylate synthase/0.591
2bbqPFGThymidylate synthase/0.566
1kceCB3Thymidylate synthase/0.559
2ftoCB3Thymidylate synthase/0.554
1aiqCB3Thymidylate synthase/0.553
1kziTHGThymidylate synthase/0.546
1tysDHFThymidylate synthase/0.539
1trgCB3Thymidylate synthase/0.532
1jtuLYBThymidylate synthase/0.530
3bgxMEFThymidylate synthase/0.529
4knzCB3Thymidylate synthase/0.529
1jutLYDThymidylate synthase/0.523
4fqsLYAThymidylate synthase ThyA/0.514
1tduCB3Thymidylate synthase/0.513
4gevCB3Thymidylate synthase/0.513
1kzjCB3Thymidylate synthase/0.512
1tduDURThymidylate synthase/0.510
1zprCB3Thymidylate synthase/0.509
1hvyD16Thymidylate synthase2.1.1.450.504
1ju6LYAThymidylate synthase2.1.1.450.501
4fogC2FThymidylate synthase ThyA/0.501
1dduCB3Thymidylate synthase/0.499
1f4fTP3Thymidylate synthase/0.496
2tscCB3Thymidylate synthase/0.496
1tsdF89Thymidylate synthase/0.492
1an5CB3Thymidylate synthase/0.485
3k2hLYABifunctional dihydrofolate reductase-thymidylate synthase/0.483
4ez8DHFThymidylate synthase2.1.1.450.475
3uwlFOZThymidylate synthase/0.474
3bhlTHGThymidylate synthase/0.473
1f4gTP4Thymidylate synthase/0.471
1jujLYAThymidylate synthase2.1.1.450.468
4foxD16Thymidylate synthase ThyA/0.467
1f28F89Thymidylate synthase2.1.1.450.466
1qzfCB3Bifunctional dihydrofolate reductase-thymidylate synthase/0.466
1bq1CB3Thymidylate synthase/0.464
2kceD16Thymidylate synthase/0.459
4isk1JYThymidylate synthase/0.454
3bhrTHGThymidylate synthase/0.452
4eb4D16Thymidylate synthase2.1.1.450.444
4eilCB3Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442