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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5e9eANPMyosin heavy chain kinase A2.7.11.7

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5e9eANPMyosin heavy chain kinase A2.7.11.71.000
4zs4ATPMyosin heavy chain kinase A2.7.11.70.630
3llaACPMyosin heavy chain kinase A2.7.11.70.619
4zmeADNMyosin heavy chain kinase A2.7.11.70.597
3pdtADPMyosin heavy chain kinase A2.7.11.70.582
3lmhADPMyosin heavy chain kinase A2.7.11.70.573
3lmiATPMyosin heavy chain kinase A2.7.11.70.525
1ia9ANPTransient receptor potential cation channel subfamily M member 72.7.11.10.511
2owb626Serine/threonine-protein kinase PLK12.7.11.210.463
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.461
1obnASVIsopenicillin N synthase1.21.3.10.459
3d5wADPSerine/threonine-protein kinase PLK/0.455
2v57PRLTetR family transcriptional regulator/0.450
2y6fM9FIsopenicillin N synthase1.21.3.10.447
3rtnRTNBeta-secretase 13.4.23.460.447
2jb4A14Isopenicillin N synthase1.21.3.10.446
1qjfACSIsopenicillin N synthase1.21.3.10.444
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.443
3ufl508Beta-secretase 13.4.23.460.442
1blzACVIsopenicillin N synthase1.21.3.10.440
3zkyWT4Isopenicillin N synthase1.21.3.10.440