Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4xlvACPInsulin receptor2.7.10.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4xlvACPInsulin receptor2.7.10.11.000
4qnyANPMitogen activated protein kinase, putative/0.508
4qmlANPSerine/threonine-protein kinase 242.7.11.10.484
1jkkANPDeath-associated protein kinase 12.7.11.10.483
3gu7ADPDeath-associated protein kinase 12.7.11.10.482
3bu5ATPInsulin receptor2.7.10.10.481
3dqwAGSProto-oncogene tyrosine-protein kinase Src2.7.10.20.476
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.462
4eooATPCyclin-dependent kinase 22.7.11.220.462
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.455
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.452
1i44ACPInsulin receptor2.7.10.10.451
4ii5ADPCyclin-dependent kinase 22.7.11.220.451
3c4zADPRhodopsin kinase/0.449
2w4jADPDeath-associated protein kinase 12.7.11.10.447
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.447
4j99ACPFibroblast growth factor receptor 2/0.446
4s33ANPMitogen-activated protein kinase 12.7.11.240.446
2qoqANPEphrin type-A receptor 32.7.10.10.445
1qmzATPCyclin-dependent kinase 22.7.11.220.444
1ig1ANPDeath-associated protein kinase 12.7.11.10.443
2j0lANPFocal adhesion kinase 12.7.10.20.443
2yaaATPDeath-associated protein kinase 2/0.442
2ijmADPFocal adhesion kinase 12.7.10.20.441
1jklANPDeath-associated protein kinase 12.7.11.10.440
2z7qACPRibosomal protein S6 kinase alpha-12.7.11.10.440