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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4r5wXAVPoly [ADP-ribose] polymerase 12.4.2.30

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4r5wXAVPoly [ADP-ribose] polymerase 12.4.2.301.000
1uk0FRMPoly [ADP-ribose] polymerase 12.4.2.300.573
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.565
4tvj09LPoly [ADP-ribose] polymerase 22.4.2.300.562
4l6s1WQPoly [ADP-ribose] polymerase 12.4.2.300.552
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.517
1uk1FRQPoly [ADP-ribose] polymerase 12.4.2.300.514
4hhy15RPoly [ADP-ribose] polymerase 12.4.2.300.512
2rcwAAIPoly [ADP-ribose] polymerase 12.4.2.300.496
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.494
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.485
3l3lL3LPoly [ADP-ribose] polymerase 12.4.2.300.476
2rd678PPoly [ADP-ribose] polymerase 12.4.2.300.475
4gv25MEPoly [ADP-ribose] polymerase 32.4.2.300.472
3gn73GNPoly [ADP-ribose] polymerase 12.4.2.300.463
3l3mA92Poly [ADP-ribose] polymerase 12.4.2.300.462
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.452
5dsyUHBPoly [ADP-ribose] polymerase 22.4.2.300.440