Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4p13FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.7

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4p13FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.71.000
3mddFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.564
3oibFDAPutative acyl-CoA dehydrogenase/0.535
2ix5FADAcyl-coenzyme A oxidase 4, peroxisomal1.3.3.60.530
1jqiFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial/0.518
2pg0FADAcyl-CoA dehydrogenase/0.517
5ahsFADAcyl-CoA dehydrogenase/0.505
4y9lFADAcyl-CoA dehydrogenase family member 11/0.491
2fznFADBifunctional protein PutA1.5.5.20.461
3qlsNDPDihydrofolate reductase1.5.1.30.461
1yb5NAPQuinone oxidoreductase1.6.5.50.456
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.454
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.453
2pswCOAN-alpha-acetyltransferase 50/0.451
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.450
2uuvFADAlkyldihydroxyacetonephosphate synthase2.5.1.260.450
3v9y24LPeroxisome proliferator-activated receptor gamma/0.450
4iqgNAPShort-chain dehydrogenase/reductase SDR/0.450
2po7CHDFerrochelatase, mitochondrial4.99.1.10.449
2y0mACOHistone acetyltransferase KAT8/0.449
2w3bNDPDihydrofolate reductase1.5.1.30.447
3gw9VNILanosterol 14-alpha-demethylase/0.447
4jldADPAdenylate kinase/0.447
2xy3DUPSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.446
1osvCHCBile acid receptor/0.445
1ot7IU5Bile acid receptor/0.445
3e2sFADBifunctional protein PutA1.5.5.20.445
3b70NAPEnoyl reductase LovC10.443
4ambDUDPutative glycosyl transferase/0.443
4typAP5Adenylate kinase/0.443
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.442
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
1in5ADPHolliday junction ATP-dependent DNA helicase RuvB/0.441
3gqvNAPEnoyl reductase LovC10.441
3qlrNDPDihydrofolate reductase1.5.1.30.440
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.440