sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 1.000 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.709 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.705 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.700 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.688 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.686 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.683 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.678 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.676 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.675 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.669 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.667 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.665 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.664 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.663 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.662 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.650 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.647 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.643 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.642 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.638 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.632 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.628 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.625 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.620 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.616 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.616 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.611 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.580 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.536 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.518 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.504 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.501 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.492 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.479 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.476 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.474 | |
| 3u9e | COA | Lmo1369 protein | / | 0.474 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.474 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.470 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.467 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.463 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.462 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.460 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.458 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.458 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.457 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.456 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.454 | |
| 4xj4 | 3AT | Cyclic GMP-AMP synthase | / | 0.454 | |
| 1ee9 | NAD | Methylenetetrahydrofolate dehydrogenase [NAD(+)] | 1.5.1.15 | 0.452 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.452 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.452 | |
| 4qq3 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.451 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.449 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.448 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.447 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.446 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.446 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.445 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.445 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.445 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.444 | |
| 3zuy | TCH | Transporter | / | 0.444 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 4px9 | ADP | ATP-dependent RNA helicase DDX3X | 3.6.4.13 | 0.443 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.442 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.442 | |
| 2y4g | TIR | TamL | / | 0.441 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4h6p | FMN | Chromate reductase | / | 0.441 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.440 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.440 |