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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4j2wFADKynurenine 3-monooxygenase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4j2wFADKynurenine 3-monooxygenase/1.000
4j31FADKynurenine 3-monooxygenase/0.627
4j36FADKynurenine 3-monooxygenase/0.613
4j33FADKynurenine 3-monooxygenase/0.605
4j34FADKynurenine 3-monooxygenase/0.600
3rp8FADFAD-dependent urate hydroxylase/0.444