Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4iv0SAMPhosphoethanolamine N-methyltransferase, putative

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4iv0SAMPhosphoethanolamine N-methyltransferase, putative/1.000
4mwzSAMPhosphoethanolamine N-methyltransferase, putative/0.666
3uj7SAMPhosphoethanolamine N-methyltransferase/0.559
3uj8SFGPhosphoethanolamine N-methyltransferase/0.556
4r6xSAHPhosphoethanolamine N-methyltransferase/0.552
4fgzSAHPhosphoethanolamine N-methyltransferase/0.524
4iv8SAMPhosphoethanolamine N-methyltransferase,putative/0.504
1ve3SAMUncharacterized protein/0.494
3ha5SFGHydroxymycolate synthase MmaA42.1.10.489
2fk8SAMHydroxymycolate synthase MmaA42.1.10.484
5epeSAHUncharacterized protein/0.481
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.478
3p9kSAHCaffeic acid O-methyltransferase/0.474
1w4xFADPhenylacetone monooxygenase1.14.13.920.470
5bp7SAHSAM-dependent methyltransferase/0.469
2ylzFADPhenylacetone monooxygenase1.14.13.920.467
5bw4SAMUncharacterized protein/0.463
2yxuATPPyridoxal kinase2.7.1.350.458
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.455
4qtuSAM18S rRNA (guanine(1575)-N(7))-methyltransferase/0.454
1qanSAHrRNA adenine N-6-methyltransferase2.1.1.1840.451
4kcfAKMFAD-dependent oxidoreductase/0.451
3ha3SAHHydroxymycolate synthase MmaA42.1.10.450
3q44D50M1 family aminopeptidase3.4.110.450
5je2SAHMethyl transferase/0.449
5bsgNAPPyrroline-5-carboxylate reductase/0.448
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.447
4i421HA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.447
3abaFLICytochrome P450/0.446
3q43D66M1 family aminopeptidase3.4.110.446
5icfSAH(S)-norcoclaurine 6-O-methyltransferase/0.446
4qzuRTLRetinol-binding protein 2/0.445
1fm4DXCMajor pollen allergen Bet v 1-L/0.444
3kpkFADSulfide-quinone reductase/0.444
5je3SAHMethyl transferase/0.444
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
3oadLPORenin3.4.23.150.442
3sr4TT8Histone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.442
3jskAHZThiamine thiazole synthase/0.441
3keuATPPyridoxal kinase2.7.1.350.441
4obwSAM2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial/0.441
1kqwRTLCellular retinol-binding protein type II/0.440
2rgoFADAlpha-Glycerophosphate Oxidase/0.440
4i4z2NE1,4-dihydroxy-2-naphthoyl-CoA synthase/0.440