scPDB - Distribution of Binding site Similarity values of 4gh1 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4gh1	0WX	Queuine tRNA-ribosyltransferase	2.4.2.29

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4gh1	0WX	Queuine tRNA-ribosyltransferase	2.4.2.29	1.000
3sm0	AEK	Queuine tRNA-ribosyltransferase	2.4.2.29	0.787
4gg9	0WW	Queuine tRNA-ribosyltransferase	2.4.2.29	0.765
4gh3	0EV	Queuine tRNA-ribosyltransferase	2.4.2.29	0.711
3ge7	AFQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.673
4fps	0UX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.650
1q63	AIQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.646
4gkt	0O1	Queuine tRNA-ribosyltransferase	2.4.2.29	0.631
1y5v	NE8	Queuine tRNA-ribosyltransferase	2.4.2.29	0.617
4gi4	0EX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.605
1q65	BHB	Queuine tRNA-ribosyltransferase	2.4.2.29	0.596
1y5x	E89	Queuine tRNA-ribosyltransferase	2.4.2.29	0.587
4giy	0WY	Queuine tRNA-ribosyltransferase	2.4.2.29	0.577
4fr1	0V2	Queuine tRNA-ribosyltransferase	2.4.2.29	0.573
1k4g	AIQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.571
1y5w	NEZ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.565
1q66	KMB	Queuine tRNA-ribosyltransferase	2.4.2.29	0.544
4q8p	CKR	Queuine tRNA-ribosyltransferase	2.4.2.29	0.531
1k4h	APQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.529
3gc4	AAQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.522
1efz	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.518
2z1w	BDI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.515
4fsa	0V3	Queuine tRNA-ribosyltransferase	2.4.2.29	0.514
2z1x	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.510
1n2v	BDI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.500
2qzr	S79	Queuine tRNA-ribosyltransferase	2.4.2.29	0.499
3gc5	2MQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.486
1f3e	DPZ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.484
2bbf	344	Queuine tRNA-ribosyltransferase	2.4.2.29	0.481
1q4w	DQU	Queuine tRNA-ribosyltransferase	2.4.2.29	0.476
2g28	TDK	Pyruvate dehydrogenase E1 component	1.2.4.1	0.472
3n87	N87	3-dehydroquinate dehydratase	4.2.1.10	0.471
1efy	BZC	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.469
3rsv	3RS	Beta-secretase 1	3.4.23.46	0.467
3cow	52H	Pantothenate synthetase	6.3.2.1	0.465
4b78	KGG	Beta-secretase 1	3.4.23.46	0.462
4gmg	NAP	Yersiniabactin biosynthetic protein YbtU	/	0.462
2ivp	ATP	tRNA N6-adenosine threonylcarbamoyltransferase	/	0.460
1ve3	SAM	Uncharacterized protein	/	0.459
4h3f	10O	Beta-secretase 1	3.4.23.46	0.459
3sn6	P0G	Beta-2 adrenergic receptor	/	0.459
4g95	OAG	Dihydrofolate reductase	1.5.1.3	0.458
2ydo	ADN	Adenosine receptor A2a	/	0.455
1kru	IPT	Galactoside O-acetyltransferase	2.3.1.18	0.454
3ts1	TYA	Tyrosine--tRNA ligase	6.1.1.1	0.452
2io6	330	Wee1-like protein kinase	2.7.10.2	0.451
3blo	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.451
4da8	BG2	Purine nucleoside phosphorylase DeoD-type	2.4.2.1	0.451
4hsh	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.451
2gev	COK	Pantothenate kinase	2.7.1.33	0.450
3ig6	438	Urokinase-type plasminogen activator	3.4.21.73	0.450
3p9k	SAH	Caffeic acid O-methyltransferase	/	0.450
1nbi	SAM	Glycine N-methyltransferase	2.1.1.20	0.449
1zdw	FLV	Prenyltransferase	/	0.448
3oaf	OAG	Dihydrofolate reductase	1.5.1.3	0.448
3ivx	FG6	Pantothenate synthetase	6.3.2.1	0.447
2dxi	ATP	Glutamate--tRNA ligase	6.1.1.17	0.446
3n1s	5GP	Purine nucleoside phosphoramidase	/	0.446
1t4c	COA	Formyl-CoA:oxalate CoA-transferase	/	0.445
2bf4	FMN	NADPH--cytochrome P450 reductase	/	0.445
3p3z	P3Z	Putative cytochrome P450	/	0.445
4fri	DWA	Beta-secretase 1	3.4.23.46	0.445
4gcx	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.445
4gki	0JN	Aminoglycoside 3'-phosphotransferase AphA1-IAB	/	0.445
4req	5AD	Methylmalonyl-CoA mutase large subunit	5.4.99.2	0.445
2yac	937	Serine/threonine-protein kinase PLK1	2.7.11.21	0.444
3isj	A8D	Pantothenate synthetase	6.3.2.1	0.444
1k7f	IAV	Tryptophan synthase alpha chain	/	0.443
2xiq	5AD	Methylmalonyl-CoA mutase, mitochondrial	/	0.443
2fb8	215	Serine/threonine-protein kinase B-raf	2.7.11.1	0.442
3aw9	GDU	NAD-dependent epimerase/dehydratase	/	0.442
4o4e	ATP	Kinase	/	0.442
2gqf	FAD	Uncharacterized protein HI_0933	/	0.441
4b1e	6T6	Beta-secretase 1	3.4.23.46	0.441
4wo5	324	Serine/threonine-protein kinase B-raf	2.7.11.1	0.441
2z7h	GG3	Geranylgeranyl pyrophosphate synthase	/	0.440
4af6	FAD	Ferredoxin--NADP reductase, leaf isozyme, chloroplastic	1.18.1.2	0.440