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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4gdpFADPolyamine oxidase FMS1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4gdpFADPolyamine oxidase FMS1/1.000
3bi2FADPolyamine oxidase FMS1/0.617
3cndFADPolyamine oxidase FMS1/0.611
3bi5FADPolyamine oxidase FMS1/0.598
3cn8FADPolyamine oxidase FMS1/0.576
1xpqFADPolyamine oxidase FMS1/0.568
4echFADPolyamine oxidase FMS1/0.566
2hkoFADLysine-specific histone demethylase 1A10.560
4fwjFADLysine-specific histone demethylase 1B10.535
3cntFADPolyamine oxidase FMS1/0.531
2uxxFAJLysine-specific histone demethylase 1A10.527
1rsgFADPolyamine oxidase FMS1/0.525
2iw5FADLysine-specific histone demethylase 1A10.523
2vvlFADMonoamine oxidase N1.4.3.40.523
4xbfFADLysine-specific histone demethylase 1A10.516
1z6lFADPolyamine oxidase FMS1/0.515
2yg4FADPutrescine oxidase/0.512
4gutFADLysine-specific histone demethylase 1B10.512
3kpfFADPolyamine oxidase1.5.3.140.504
2yg5FADPutrescine oxidase/0.499
1h83FADPolyamine oxidase1.5.3.140.496
2dw4FADLysine-specific histone demethylase 1A10.496
4guuFA9Lysine-specific histone demethylase 1B10.492
2yg7FADPutrescine oxidase/0.485
3zdnFADMonoamine oxidase N1.4.3.40.485
1h81FADPolyamine oxidase1.5.3.140.481
2jaeFADL-amino acid oxidase/0.481
3k7mFAD6-hydroxy-L-nicotine oxidase/0.479
3rhaFDAPutrescine oxidase/0.472
3k7tFAD6-hydroxy-L-nicotine oxidase/0.469
4fweFADLysine-specific histone demethylase 1B10.466
2yg3FADPutrescine oxidase/0.464
2e1mFADL-glutamate oxidase/0.447
3we0FADLysine 2-monooxygenase/0.441
4kx6FADFumarate reductase flavoprotein subunit1.3.5.40.440