sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ffb | GTP | Tubulin alpha-1 chain |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4ffb | GTP | Tubulin alpha-1 chain | / | 1.000 | |
| 4wbn | GTP | Tubulin alpha-1B chain | / | 0.570 | |
| 4ihj | GTP | Tubulin alpha-1B chain | / | 0.567 | |
| 4zol | GTP | Tubulin alpha-1B chain | / | 0.556 | |
| 5la6 | GTP | Tubulin alpha-1B chain | / | 0.553 | |
| 4tv9 | GTP | Tubulin alpha-1B chain | / | 0.543 | |
| 4o4i | GTP | Tubulin alpha-1B chain | / | 0.529 | |
| 4tuy | GTP | Tubulin alpha-1B chain | / | 0.527 | |
| 4o4l | GTP | Tubulin alpha-1B chain | / | 0.517 | |
| 5jqg | GTP | Tubulin alpha-1B chain | / | 0.516 | |
| 3ryh | GTP | Tubulin alpha chain | / | 0.500 | |
| 4iij | GTP | Tubulin alpha-1B chain | / | 0.496 | |
| 4u3j | GTP | Tubulin beta chain | / | 0.477 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.453 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.452 | |
| 2xfy | ACX | Beta-amylase | 3.2.1.2 | 0.449 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.447 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.447 | |
| 3tut | ATP | RNA 3'-terminal phosphate cyclase | 6.5.1.4 | 0.446 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.444 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.442 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.441 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4tyq | AP5 | Adenylate kinase | / | 0.441 | |
| 1e81 | M91 | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.440 |