Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4dl9NADS-(hydroxymethyl)glutathione dehydrogenase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4dl9NADS-(hydroxymethyl)glutathione dehydrogenase/1.000
4jjiNADAlcohol dehydrogenase class-3/0.630
4dlbNADS-(hydroxymethyl)glutathione dehydrogenase/0.626
3ukoNADAlcohol dehydrogenase class-3/0.583
4gl4NAIAlcohol dehydrogenase class-3/0.570
1ma0NADAlcohol dehydrogenase class-31.1.1.10.555
2fzeAPRAlcohol dehydrogenase class-31.1.1.10.552
4c4oNADSADH/0.485
1adbCNDAlcohol dehydrogenase E chain1.1.1.10.484
1tehNADAlcohol dehydrogenase class-31.1.1.10.484
1adcPADAlcohol dehydrogenase E chain1.1.1.10.482
1e3lNADAlcohol dehydrogenase 41.1.1.10.482
1f8fNADBenzyl alcohol dehydrogenase/0.471
1a71NADAlcohol dehydrogenase E chain1.1.1.10.462
2jhfNADAlcohol dehydrogenase E chain1.1.1.10.461
1cdoNADAlcohol dehydrogenase 11.1.1.10.460
2xaaNADSecondary alcohol dehydrogenase/0.458
1agnNADAlcohol dehydrogenase class 4 mu/sigma chain1.1.1.10.450
4dwvNAJAlcohol dehydrogenase E chain1.1.1.10.450
1ht0NADAlcohol dehydrogenase 1C1.1.1.10.447
2oxiNADAlcohol dehydrogenase E chain1.1.1.10.447
4nfhNAJAlcohol dehydrogenase E chain1.1.1.10.446
2fzwNADAlcohol dehydrogenase class-31.1.1.10.442
4ng5NAJAlcohol dehydrogenase E chain1.1.1.10.441