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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4cb629RPolymerase basic protein 2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4cb629RPolymerase basic protein 2/1.000
5fmmMGTPolymerase basic protein 2/0.582
2vqzMGTPolymerase basic protein 2/0.533
4cb593GPolymerase basic protein 2/0.528
4cb4MGTPolymerase basic protein 2/0.514
4nceMGTPolymerase basic protein 2/0.514
4eqkMGTPolymerase basic protein 2/0.490
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.479
4es5MGTPolymerase basic protein 2/0.478
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.477
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.464
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.464
1pj6FOLDimethylglycine oxidase1.5.3.100.460
3ug8IMNAldo-keto reductase family 1 member C3/0.460
4cb741GPolymerase basic protein 2/0.460
4nv1TYDFormyl transferase/0.459
1u65CP0Acetylcholinesterase3.1.1.70.452
1uhjCZBAequorin-2/0.450
4nv10FXFormyl transferase/0.450
1ut6A8NAcetylcholinesterase3.1.1.70.449
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.448
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.443
2gesCOKPantothenate kinase2.7.1.330.442
3lm1LECAgglutinin alpha chain/0.441
3v0o4GWHisto-blood group ABO system transferase/0.441
4yfy0FXVioF/0.441
4dbw511Aldo-keto reductase family 1 member C3/0.440