Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.21.000
3vo2FADFerredoxin--NADP reductase/0.676
3zc3FADFerredoxin--NADP reductase1.18.1.20.635
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.628
1bx1FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.627
2b5oFADFerredoxin--NADP reductase1.18.1.20.623
1fnbFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.616
1gawFADFerredoxin/0.616
1h42FADFerredoxin--NADP reductase1.18.1.20.612
1gjrFADFerredoxin--NADP reductase1.18.1.20.609
1sm4FADFerredoxin--NADP reductase/0.602
1fncFDAFerredoxin--NADP reductase, chloroplastic1.18.1.20.596
1w35FADFerredoxin--NADP reductase1.18.1.20.592
1gaqFADFerredoxin/0.589
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.589
1bjkFADFerredoxin--NADP reductase1.18.1.20.586
1e62FADFerredoxin--NADP reductase1.18.1.20.583
1go2FADFerredoxin--NADP reductase1.18.1.20.583
4bprFADFerredoxin--NADP reductase1.18.1.20.583
3fpkFADFerredoxin-NADP reductase/0.582
3zbtFADFerredoxin--NADP reductase1.18.1.20.581
4c43FADFerredoxin--NADP reductase1.18.1.20.578
1ogiFADFerredoxin--NADP reductase1.18.1.20.575
1qgyFADFerredoxin--NADP reductase1.18.1.20.572
2ok8FADFerredoxin--NADP reductase, apicoplast/0.572
1e64FADFerredoxin--NADP reductase1.18.1.20.571
3w5uFADFerredoxin/0.567
1queFADFerredoxin--NADP reductase1.18.1.20.565
1w87FADFerredoxin--NADP reductase1.18.1.20.563
2rc6FADFerredoxin--NADP reductase/0.559
1qh0FADFerredoxin--NADP reductase1.18.1.20.558
1gvhFADFlavohemoprotein/0.555
1ewyFADFerredoxin--NADP reductase1.18.1.20.550
1fndFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.550
1h85FADFerredoxin--NADP reductase1.18.1.20.550
3qe2FADNADPH--cytochrome P450 reductase/0.547
4yaoFADNADPH--cytochrome P450 reductase/0.545
4y9uFADNADPH--cytochrome P450 reductase/0.540
4uajFADNa(+)-translocating NADH-quinone reductase subunit F/0.538
4y7cFADNADPH--cytochrome P450 reductase/0.537
1amoFADNADPH--cytochrome P450 reductase/0.535
1gr1FADFerredoxin--NADP reductase1.18.1.20.535
1ja1FADNADPH--cytochrome P450 reductase/0.530
1j9zFADNADPH--cytochrome P450 reductase/0.523
1ogjFADFerredoxin--NADP reductase1.18.1.20.519
1bx0FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.518
1e63FADFerredoxin--NADP reductase1.18.1.20.518
3qfcFADNADPH--cytochrome P450 reductase/0.517
1b2rFADFerredoxin--NADP reductase1.18.1.20.515
3jqrFADFerredoxin--NADP reductase, apicoplast/0.514
2rc5FADFerredoxin--NADP reductase/0.509
2piaFMNPhthalate dioxygenase reductase/0.507
3qftFADNADPH--cytochrome P450 reductase/0.507
2bpoFADNADPH--cytochrome P450 reductase/0.505
3qfsFADNADPH--cytochrome P450 reductase/0.501
3ojxFADNADPH--cytochrome P450 reductase/0.499
1qgzFADFerredoxin--NADP reductase1.18.1.20.494
1fdrFADFerredoxin--NADP reductase1.18.1.20.490
2bf4FADNADPH--cytochrome P450 reductase/0.487
4yafFADNADPH--cytochrome P450 reductase/0.487
4jlj1NMDeoxycytidine kinase2.7.1.740.486
2r6hFADNa(+)-translocating NADH-quinone reductase subunit F/0.480
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.474
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.473
2xncFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.473
1cqxFADFlavohemoprotein/0.471
1f20FADNitric oxide synthase, brain1.14.13.390.470
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.470
4jlm1NNDeoxycytidine kinase2.7.1.740.469
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.466
4b4vL34Bifunctional protein FolD/0.465
1tllFADNitric oxide synthase, brain1.14.13.390.464
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.464
3ske054Genome polyprotein2.7.7.480.463
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.463
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.463
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.462
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.461
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.459
4b4w9L9Bifunctional protein FolD/0.459
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.458
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.458
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.458
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
3hl0NADMaleylacetate reductase/0.456
2cndFADNitrate reductase [NADH]1.7.1.10.455
2e94364Geranylgeranyl pyrophosphate synthase/0.454
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.451
4uy6SAHHistidine N-alpha-methyltransferase/0.451
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.450
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.450
1krhFADBenzoate 1,2-dioxygenase electron transfer component1.18.1.30.449
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.449
4fk8FADFerredoxin--NADP reductase/0.449
4n4wSNTSmoothened homolog/0.449
2vn1FK5Peptidylprolyl isomerase/0.448
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
5a4vQUEGlutathione S-transferase F22.5.1.180.448
1x1dSAHC-20 methyltransferase/0.447
3c1oNAPEugenol synthase/0.447
3ha7B32Hydroxymycolate synthase MmaA42.1.10.447
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.447
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.446
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
3ojxFMNNADPH--cytochrome P450 reductase/0.446
4phlPILPhosphodiesterase/0.446
4y9rFADNADPH--cytochrome P450 reductase/0.446
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.445
3gynB42Genome polyprotein2.7.7.480.445
4rvfTYDD-mycarose 3-C-methyltransferase/0.445
4tm1FDAKtzI/0.444
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
1g6oADPCag alpha/0.442
1pqc444Oxysterols receptor LXR-beta/0.442
1w34FADFerredoxin--NADP reductase1.18.1.20.442
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.442
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.442
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
1s9dAFBCytohesin-2/0.441
1s9dAFBADP-ribosylation factor 1/0.441
1tilATPAnti-sigma F factor/0.441
2vnjFADNADPH:ferredoxin reductase/0.441
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.441
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440