Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4a7zAY9Aldos-2-ulose dehydratase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4a7zAY9Aldos-2-ulose dehydratase/1.000
4a7yNHFAldos-2-ulose dehydratase/0.682
1esmCOAPantothenate kinase2.7.1.330.488
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.486
4n9qFMNFMN-dependent NADH-azoreductase 1/0.481
4nv10FXFormyl transferase/0.481
4nv1TYDFormyl transferase/0.478
4nv14TGFormyl transferase/0.467
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.464
3af2ACPPantothenate kinase2.7.1.330.463
2zsaADPPantothenate kinase2.7.1.330.457
2idvM7GEukaryotic translation initiation factor 4E-1/0.456
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.456
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.455
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.454
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.454
4f1yCNIGlutamate receptor 3/0.454
2cekN8TAcetylcholinesterase3.1.1.70.453
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.452
3aezGDPPantothenate kinase2.7.1.330.452
4cb629RPolymerase basic protein 2/0.452
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.451
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.450
3juoAJDPhenazine biosynthesis protein A/B/0.449
1gpnHUBAcetylcholinesterase3.1.1.70.448
3dziRGTADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.448
1lb9DNQGlutamate receptor 2/0.447
4dya0MFNucleoprotein/0.447
1pqc444Oxysterols receptor LXR-beta/0.445
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.445
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.444
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.444
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.443
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.443
4hhy15RPoly [ADP-ribose] polymerase 12.4.2.300.442
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.441
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.441
4dk70KSOxysterols receptor LXR-beta/0.441
2xjeU5PCytosolic purine 5'-nucleotidase3.1.3.50.440