sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 1.000 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.458 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.458 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.457 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.457 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4j7h | TRH | PCZA361.3 | / | 0.455 | |
| 1n2g | APC | Pantothenate synthetase | 6.3.2.1 | 0.452 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.452 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.451 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.449 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4nau | AGS | Phosphopantetheine adenylyltransferase | / | 0.449 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.447 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.447 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.447 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.446 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.446 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.446 | |
| 3w8r | ACP | Uridine kinase | / | 0.444 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.443 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.443 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.442 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.442 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.441 | |
| 5dp2 | NAP | CurF | / | 0.441 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.440 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.440 |