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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3t113T1Gag-Pol polyprotein3.4.23.16

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3t113T1Gag-Pol polyprotein3.4.23.161.000
3nwq2NCGag-Pol polyprotein3.4.23.160.580
3nwxKVSGag-Pol polyprotein3.4.23.160.564
3nxe2NCProtease/0.556
1k6tXN1Gag-Pol polyprotein3.4.23.160.555
1k6cMK1Gag-Pol polyprotein3.4.23.160.553
1k6pXN3Gag-Pol polyprotein3.4.23.160.549
1k6vXN2Gag-Pol polyprotein3.4.23.160.543
3el01UNGag-Pol polyprotein3.4.23.160.543
3bheBZNGag-Pol polyprotein3.4.23.160.542
1xl2189Gag-Pol polyprotein3.4.23.160.539
2pwcG3GGag-Pol polyprotein3.4.23.160.534
3cktYDPGag-Pol polyprotein3.4.23.160.528
2p3b3TLV-1 PROTEASE protein/0.527
2p3b3TLV-1 protease/0.527
3kfs3TLGag-Pol polyprotein/0.527
2r3wG3GGag-Pol polyprotein3.4.23.160.526
3aidARQGag-Pol polyprotein3.4.23.160.526
3kf03TLGag-Pol polyprotein/0.526
1ivp1ZKGag-Pol polyprotein/0.525
2bpv1INGag-Pol polyprotein3.4.23.160.524
2qnqQN3Gag-Pol polyprotein3.4.23.160.522
2qhcAB1Protease/0.521
2aquDR7Gag-Pol polyprotein3.4.23.160.520
3el51UNGag-Pol polyprotein/0.520
3qbfJHGGag-Pol polyprotein3.4.23.160.520
2nmyROCProtease/0.519
2xyeCXGGag-Pol polyprotein/0.517
3tl9ROCGag-Pol polyprotein3.4.23.160.517
4ye3G04Gag-Pol polyprotein3.4.23.160.517
3zptM8YGag-Pol polyprotein3.4.23.160.515
4k4p3TLGag-Pol polyprotein/0.515
1ec3MS3Gag-Pol polyprotein3.4.23.160.514
2pqzG0GGag-Pol polyprotein3.4.23.160.514
2r43G3GGag-Pol polyprotein3.4.23.160.513
3bxsDRSGag-Pol polyprotein3.4.23.160.512
2aidTHKGag-Pol polyprotein3.4.23.160.511
2r3tG4GGag-Pol polyprotein3.4.23.160.511
3cyxROCGag-Pol polyprotein3.4.23.160.511
3qrmNK7Gag-Pol polyprotein3.4.23.160.511
2qnnQN1Gag-Pol polyprotein3.4.23.160.510
3kfr3TLGag-Pol polyprotein/0.509
3oxxDR7Gag-Pol polyprotein3.4.23.160.509
3qp0NI8Gag-Pol polyprotein3.4.23.160.509
1t7kBH0Gag-Pol polyprotein3.4.23.160.508
3sa323XProtease/0.508
2hc0AB2Protease/0.507
2pyn1UNGag-Pol polyprotein3.4.23.160.507
1ida0POGag-Pol polyprotein3.4.23.470.506
1sbgIM1Gag-Pol polyprotein/0.506
2r5q1UNGag-Pol polyprotein/0.506
3pwrROCGag-Pol polyprotein3.4.23.160.506
1d4yTPVGag-Pol polyprotein3.4.23.160.505
1hsgMK1Gag-Pol polyprotein/0.505
3sa5A69Protease/0.505
3zpuM8BGag-Pol polyprotein3.4.23.160.505
4j5j478Gag-Pol polyprotein3.4.23.160.505
2qhyMZ1Gag-Pol polyprotein/0.504
3sa9A68Protease/0.504
3ttp017Gag-Pol polyprotein3.4.23.160.504
1jld0PPGag-Pol polyprotein/0.503
2pym1UNGag-Pol polyprotein3.4.23.160.503
3linE13Protease/0.503
3s43478Protease/0.503
3s54017Protease/0.503
4a6bQG8Gag-Pol polyprotein3.4.23.160.503
4j55031Gag-Pol polyprotein3.4.23.160.503
2bb9AKCGag-Pol polyprotein3.4.23.160.502
2qi0MZ3Gag-Pol polyprotein/0.502
3nu9478Gag-Pol polyprotein3.4.23.160.502
1hvhQ82Gag-Pol polyprotein3.4.23.160.501
1hxwRITGag-Pol polyprotein/0.501
2qi6MZ8Gag-Pol polyprotein/0.501
4djqM86Pol polyprotein/0.501
1ec2BEJGag-Pol polyprotein3.4.23.160.500
2nnpROCProtease/0.500
2xyfG40Gag-Pol polyprotein/0.500
2a4fAAUV-1 protease/0.499
3vfa031Gag-Pol polyprotein3.4.23.160.499
1ajxAH1Gag-Pol polyprotein3.4.23.160.498
1z1rHBHGag-Pol polyprotein3.4.23.160.498
2bqvA1AProtease/0.498
3ggxGGXGag-Pol polyprotein/0.498
3qrsNK8Gag-Pol polyprotein3.4.23.160.498
1ec0BEDGag-Pol polyprotein3.4.23.160.497
1hosPHPGag-Pol polyprotein/0.497
1vikBAYGag-Pol polyprotein/0.497
1wbmBLLPol protein/0.497
1z1hHBBGag-Pol polyprotein3.4.23.160.497
2qd8065Gag-Pol polyprotein3.4.23.160.497
2qi5MZ7Gag-Pol polyprotein/0.497
3o9aK14Pol polyprotein/0.497
4hdbG52Gag-Pol polyprotein3.4.23.160.497
1hshMK1Gag-Pol polyprotein/0.496
1t7i017Gag-Pol polyprotein3.4.23.160.496
2uy0HV1Gag-Pol polyprotein3.4.23.160.496
3bgbLJGGag-Pol polyprotein3.4.23.160.496
3t3c017Gag-Pol polyprotein3.4.23.160.496
1sh9RITGag-Pol polyprotein3.4.23.160.495
2f8g017Gag-Pol polyprotein3.4.23.160.495
2i4xKGQProtease/0.495
2pwrG4GGag-Pol polyprotein3.4.23.160.495
2r38G4GGag-Pol polyprotein3.4.23.160.495
3nu4478Gag-Pol polyprotein3.4.23.160.495
1izhQ50Protease/0.494
1iziQ50Gag-Pol polyprotein3.4.23.160.494
2bpz3INGag-Pol polyprotein3.4.23.160.494
3o9gF53Gag-Pol polyprotein/0.494
1ebyBEBGag-Pol polyprotein3.4.23.160.493
2cej1AHPol protein/0.493
2f80017Gag-Pol polyprotein3.4.23.160.493
2ieo017Protease/0.493
2qi3MZ5Gag-Pol polyprotein/0.493
2rkfAB1Pol protein/0.493
2wl05AHGag-Pol polyprotein/0.493
3ekwDR7Gag-Pol polyprotein3.4.23.160.493
3em4DR7Gag-Pol polyprotein3.4.23.160.493
3jvwDMPGag-Pol polyprotein3.4.23.160.493
1w5yBE6Gag-Pol polyprotein3.4.23.160.492
1yt9OISGag-Pol polyprotein/0.492
2b7zMK1Gag-Pol polyprotein/0.492
3vfb031Gag-Pol polyprotein3.4.23.160.492
9hvp0E9Gag-Pol polyprotein/0.492
1npa3NHGag-Pol polyprotein3.4.23.160.491
1npwLGZGag-Pol polyprotein3.4.23.160.491
2q54MU1Protease/0.491
3ekv478Gag-Pol polyprotein3.4.23.160.491
3gi6D78Gag-Pol polyprotein/0.491
1ebwBEIGag-Pol polyprotein3.4.23.160.490
1fej2NCGag-Pol polyprotein3.4.23.160.490
2fdd385Pol protein/0.490
1a8g2Z4Gag-Pol polyprotein3.4.23.160.489
1a9mU0EGag-Pol polyprotein/0.489
1b6pPI7Gag-Pol polyprotein3.4.23.160.489
1bv7XV6Gag-Pol polyprotein3.4.23.160.489
1daz0Q4Gag-Pol polyprotein3.4.23.160.489
1rl8RITGag-Pol polyprotein3.4.23.160.489
1sdtMK1Gag-Pol polyprotein3.4.23.160.489
1xl5190Gag-Pol polyprotein3.4.23.160.489
2fxdDR7Pol polyprotein/0.489
2wkz5AHGag-Pol polyprotein/0.489
3livE16Protease/0.489
3o9cK20Pol polyprotein/0.489
3saa77FProtease/0.489
1ec1BEEGag-Pol polyprotein3.4.23.160.488
1qbsDMPGag-Pol polyprotein3.4.23.160.488
1vijBAYGag-Pol polyprotein/0.488
3ekp478Gag-Pol polyprotein3.4.23.160.488
3oxv478Gag-Pol polyprotein3.4.23.160.488
1c6zROCProtease/0.487
1hvlA76Gag-Pol polyprotein/0.487
2p3d3TLProtease/0.487
2qak1UNGag-Pol polyprotein3.4.23.160.487
2qd7065Gag-Pol polyprotein3.4.23.160.487
2qd6065Gag-Pol polyprotein3.4.23.160.486
3a2oKNJGag-Pol polyprotein3.4.23.160.486
3o9fK2DGag-Pol polyprotein/0.486
4dqh017Gag-Pol polyprotein/0.486
1hihC20Gag-Pol polyprotein/0.485
1t7j478Gag-Pol polyprotein3.4.23.160.485
2fde385Gag-Pol polyprotein3.4.23.160.485
2qi4MZ6Gag-Pol polyprotein/0.485
3gi4K60Gag-Pol polyprotein/0.485
4dqc017Gag-Pol polyprotein/0.485
1c6yMK1Protease/0.484
1odw0E8Gag-Pol polyprotein3.4.23.160.484
1zsf0ZSGag-Pol polyprotein3.4.23.160.484
2bpy3INGag-Pol polyprotein3.4.23.160.484
3el4ROCGag-Pol polyprotein3.4.23.160.484
3fx5KNIGag-Pol polyprotein3.4.23.160.484
3qpjN4IGag-Pol polyprotein3.4.23.160.484
3zpsEQMGag-Pol polyprotein3.4.23.160.484
4hegG52Gag-Pol polyprotein3.4.23.160.484
4njt017Protease/0.484
1c6x3INProtease/0.483
1metDMPGag-Pol polyprotein3.4.23.160.483
1sduMK1Gag-Pol polyprotein3.4.23.160.483
2hb3GRLProtease/0.483
4qgiROCGag-Pol polyprotein3.4.23.160.483
1hiiC20Gag-Pol polyprotein/0.482
1k1u0Q4Gag-Pol polyprotein3.4.23.160.482
1w5vBE3Gag-Pol polyprotein3.4.23.160.482
2bpw1INGag-Pol polyprotein3.4.23.160.482
2p3a3TLPol protein/0.482
2q641UNGag-Pol polyprotein3.4.23.160.482
3em3478Gag-Pol polyprotein3.4.23.160.482
3em6017Gag-Pol polyprotein3.4.23.160.482
3liqE14Protease/0.482
3lzv017Gag-Pol polyprotein3.4.23.160.482
3sa755AProtease/0.482
3ufnROCGag-Pol polyprotein/0.482
4a6cQG9Gag-Pol polyprotein3.4.23.160.482
1b6kPI5Gag-Pol polyprotein3.4.23.160.481
1d4lPI9Gag-Pol polyprotein3.4.23.160.481
1sdvMK1Gag-Pol polyprotein3.4.23.160.481
1t3r017Gag-Pol polyprotein3.4.23.160.481
3bgcLJHGag-Pol polyprotein3.4.23.160.481
3ggu017Gag-Pol polyprotein3.4.23.160.481
3kddJZQGag-Pol polyprotein3.4.23.160.481
3kfn3TLGag-Pol polyprotein/0.481
3mws017Pol protein/0.481
3uhl2NCGag-Pol polyprotein3.4.23.160.481
4kb9G79Protease/0.481
1c70L75Protease/0.480
1k2b0Q4Gag-Pol polyprotein3.4.23.160.480
1qbu846Gag-Pol polyprotein3.4.23.160.480
1zsr0ZTGag-Pol polyprotein3.4.23.160.480
3nuo478Gag-Pol polyprotein3.4.23.160.480
3o9bK2APol polyprotein/0.480
3qn8NI7Gag-Pol polyprotein3.4.23.160.480
4hla017Gag-Pol polyprotein3.4.23.160.480
1fg62NCGag-Pol polyprotein3.4.23.160.479
1hwr216Gag-Pol polyprotein3.4.23.160.479
1odyLP1Gag-Pol polyprotein3.4.23.160.479
3d1xROCGag-Pol polyprotein3.4.23.160.479
3nyg2NCGag-Pol polyprotein3.4.23.160.479
4djoMK5Pol polyprotein/0.479
1d4kPI8Gag-Pol polyprotein3.4.23.160.478
1dw60Q4Gag-Pol polyprotein3.4.23.160.478
1fg80Q4Gag-Pol polyprotein3.4.23.160.478
1g35AHFGag-Pol polyprotein3.4.23.160.478
2qi7MZ9Gag-Pol polyprotein/0.478
2z54AB1Gag-Pol polyprotein3.4.23.160.478
3kdcJZPGag-Pol polyprotein3.4.23.160.478
3ndtROCGag-Pol polyprotein3.4.23.160.478
3o9iA61Gag-Pol polyprotein/0.478
3vf5031Gag-Pol polyprotein3.4.23.160.478
1ebzBECGag-Pol polyprotein3.4.23.160.477
1fgc2NCGag-Pol polyprotein3.4.23.160.477
1g2kNM1Gag-Pol polyprotein3.4.23.160.477
1w5xBE5Gag-Pol polyprotein3.4.23.160.477
2hs2017Protease/0.477
2i4vDJRV-1 protease/0.477
1wbk568Pol protein/0.476
4q1y017Gag-Pol polyprotein3.4.23.160.476
1fff0Q4Gag-Pol polyprotein3.4.23.160.475
1idb0DOGag-Pol polyprotein/0.475
1iiq0ZRGag-Pol polyprotein3.4.23.160.475
1mesDMPGag-Pol polyprotein3.4.23.160.475
1tcxIM1Gag-Pol polyprotein3.4.23.160.475
2hs1017Protease/0.475
2qhzMZ2Gag-Pol polyprotein/0.475
2qi1MZ4Gag-Pol polyprotein/0.475
3d1yROCGag-Pol polyprotein3.4.23.160.475
3jw2017Gag-Pol polyprotein3.4.23.160.475
3ok9G52Gag-Pol polyprotein3.4.23.160.475
3oy4017Gag-Pol polyprotein3.4.23.160.475
3sa8K83Protease/0.475
1bai0Q4Gag-Pro polyprotein/0.474
1qbrXV6Gag-Pol polyprotein3.4.23.160.474
2uxzHI1Gag-Pol polyprotein3.4.23.160.474
3djkG55Gag-Pol polyprotein3.4.23.160.474
3dk1G05Gag-Pol polyprotein3.4.23.160.474
3ekx1UNGag-Pol polyprotein3.4.23.160.474
3hzc2NCProtease/0.474
3sa6F71Protease/0.474
1a940Q4Gag-Pol polyprotein3.4.23.160.473
1ffi2NCGag-Pol polyprotein3.4.23.160.473
1msmJE2Gag-Pol polyprotein3.4.23.160.473
2bpxMK1Gag-Pol polyprotein3.4.23.160.473
2i4wKGQProtease/0.473
2p3c3TLProtease/0.473
2qci065Gag-Pol polyprotein3.4.23.160.473
3d1z017Gag-Pol polyprotein3.4.23.160.473
3dcrKVSProtease/0.473
4djpM73Pol polyprotein/0.473
4djr0KJPol polyprotein/0.473
1ff02NCGag-Pol polyprotein3.4.23.160.472
1hiv1ZKGag-Pol polyprotein/0.472
1meuDMPGag-Pol polyprotein3.4.23.160.472
2bbbHH1Gag-Pol polyprotein3.4.23.160.472
4a4qUX9Pol protein/0.472
4dqb017Gag-Pol polyprotein/0.472
1sguMK1Gag-Pol polyprotein3.4.23.160.471
2q631UNGag-Pol polyprotein3.4.23.160.471
3i7eDJRGag-Pol polyprotein/0.471
3ogqAB1Pol polyprotein/0.471
3qroNK9Gag-Pol polyprotein3.4.23.160.471
4dqe017Gag-Pol polyprotein/0.471
4i8zG08Gag-Pol polyprotein3.4.23.160.471
1b6mPI6Gag-Pol polyprotein3.4.23.160.470
1bwaXV6Gag-Pol polyprotein3.4.23.160.470
2avm2NCGag-Pol polyprotein3.4.23.160.470
3nu5478Gag-Pol polyprotein3.4.23.160.470
3st5G89Gag-Pol polyprotein3.4.23.160.470
3vf7031Gag-Pol polyprotein3.4.23.160.470
4dqf017Gag-Pol polyprotein/0.470
2q5kAB1Protease/0.469
1hpxKNIGag-Pol polyprotein/0.468
2avsMK1Gag-Pol polyprotein3.4.23.160.468
5upjUINGag-Pol polyprotein/0.468
1bdrIM1Gag-Pol polyprotein3.4.23.160.467
1mtrPI6Gag-Pol polyprotein3.4.23.160.467
1muiAB1Protease/0.467
1proA88Gag-Pol polyprotein/0.467
2upjU02Gag-Pol polyprotein3.4.23.160.467
3lixE17Protease/0.467
3oxw017Gag-Pol polyprotein3.4.23.160.467
1npvL27Gag-Pol polyprotein3.4.23.160.466
2nnkROCProtease/0.466
3i2l2NCProtease/0.466
3nu3478Gag-Pol polyprotein3.4.23.160.466
1hvrXK2Gag-Pol polyprotein/0.465
2f81017Gag-Pol polyprotein3.4.23.160.465
3mxdK53Gag-Pol polyprotein3.4.23.160.465
3pwm017Gag-Pol polyprotein3.4.23.160.465
7upjINUGag-Pol polyprotein3.4.23.160.465
2i4dQFIProtease/0.464
3d20017Gag-Pol polyprotein3.4.23.160.464
3o9dK19Pol polyprotein/0.464
2q55MU0Protease/0.463
3qaaG04Gag-Pol polyprotein3.4.23.160.463
1hpv478Gag-Pol polyprotein/0.462
3o99K13Pol polyprotein/0.462
1kzkJE2Gag-Pol polyprotein3.4.23.160.461
2avvMK1Gag-Pol polyprotein3.4.23.160.461
3ec0GRLGag-Pol polyprotein3.4.23.470.461
3nls016Gag-Pol polyprotein3.4.23.160.461
1d4sTPVGag-Pol polyprotein3.4.23.160.460
1ivq0PXGag-Pol polyprotein/0.459
3mxeK54Gag-Pol polyprotein3.4.23.160.459
1d4jMSCGag-Pol polyprotein3.4.23.160.458
1ebk0Q4Gag-Pol polyprotein3.4.23.160.458
1hbvGANGag-Pol polyprotein/0.458
2q3kMUWGag-Pol polyprotein/0.458
3i6oGR6Gag-Pol polyprotein3.4.23.160.458
1ajvNMBGag-Pol polyprotein3.4.23.160.457
1msnJE2Gag-Pol polyprotein3.4.23.160.457
2ien017Gag-Pol polyprotein3.4.23.160.457
3qihNI7Gag-Pol polyprotein3.4.23.160.457
3so9017Pol protein/0.457
3upjU03Gag-Pol polyprotein/0.457
4njsG08Protease/0.457
2b60RITPol polyprotein/0.456
2i4uDJRProtease/0.456
1merDMQGag-Pol polyprotein3.4.23.160.454
4hdpG52Gag-Pol polyprotein3.4.23.160.454
3lzu017Gag-Pol polyprotein3.4.23.160.453
1d4iBEGGag-Pol polyprotein3.4.23.160.451
2z4o065Gag-Pol polyprotein3.4.23.160.451
3jvy017Gag-Pol polyprotein3.4.23.160.451
3nu6478Gag-Pol polyprotein3.4.23.160.451
3o9eA60Pol polyprotein/0.451
1bv9XV6Gag-Pol polyprotein3.4.23.160.450
3r4b74TGag-Pol polyprotein/0.450
4hdfG52Gag-Pol polyprotein3.4.23.160.449
3bvb017Gag-Pol polyprotein3.4.23.160.448
1hpoUNIGag-Pol polyprotein3.4.23.160.447
1k2c0Q4Gag-Pol polyprotein3.4.23.160.447
1qbt146Gag-Pol polyprotein3.4.23.160.447
1bwb146Gag-Pol polyprotein3.4.23.160.446
2i0dMUTProtease/0.446
2r5pMK1Gag-Pol polyprotein/0.446
3lzs017Gag-Pol polyprotein3.4.23.160.446
3bva2NCGag-Pol polyprotein3.4.23.160.445
4q1w017Gag-Pol polyprotein3.4.23.160.445
3sabF78Protease/0.444
4dfg0JVGag-Pol polyprotein3.4.23.160.444
1u3dFADCryptochrome-1/0.443
2psuMUUProtease/0.443
3o9hK2EGag-Pol polyprotein/0.443
3ucb017Gag-Pol polyprotein/0.443
1mrwK57Gag-Pol polyprotein3.4.23.160.442
4q1x017Gag-Pol polyprotein3.4.23.160.442
1m0b0ZQGag-Pol polyprotein3.4.23.160.441
3slz3TLPutative gag-pro-pol polyprotein/0.441
1d4hBEHGag-Pol polyprotein3.4.23.160.440
3cyw017Gag-Pol polyprotein3.4.23.160.440
3litE15Protease/0.440
3nuj478Gag-Pol polyprotein3.4.23.160.440
3sacAF8Protease/0.440