Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3pm0BHFCytochrome P450 1B1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3pm0BHFCytochrome P450 1B1/1.000
4i8vBHFCytochrome P450 1A11.14.14.10.565
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.530
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.529
4j6cSTRCytochrome P450 monooxygenase/0.523
4j6bPLOCytochrome P450 monooxygenase/0.514
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.513
4ejgNCTCytochrome P450 2A131.14.14.10.493
3qm4PN0Cytochrome P450 2D6/0.490
4ejh0QACytochrome P450 2A131.14.14.10.487
2ca0PXICytochrome P450 monooxygenase PikC/0.484
4jbtASDCytochrome P450 monooxygenase/0.483
4r20AERCytochrome P450 family 17 polypeptide 2/0.478
3tdaPN0Cytochrome P450 2D6/0.476
4r21STRCytochrome P450 family 17 polypeptide 2/0.472
3a1l2CCCytochrome P450/0.471
4j6dTESCytochrome P450 monooxygenase/0.470
2vzmNRBCytochrome P450 monooxygenase PikC/0.466
2z3uCRRCytochrome P450/0.464
4y8wSTRSteroid 21-hydroxylase/0.464
2hasC3OVitamin D3 receptor/0.460
3t3q9PLCytochrome P450 2A61.14.130.460
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.459
2c7xNRBCytochrome P450 monooxygenase PikC/0.459
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.458
1yinCM3Estrogen receptor/0.456
1bk0ACVIsopenicillin N synthase1.21.3.10.455
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.453
4rupH97Vitamin D3 receptor A/0.452
2bxoOPBSerum albumin/0.451
3k4nFADPyranose 2-oxidase/0.451
3q44D50M1 family aminopeptidase3.4.110.451
4xldBRLPeroxisome proliferator-activated receptor gamma/0.450
3p6pA6BCamphor 5-monooxygenase1.14.15.10.449
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.447
2hb7O1CVitamin D3 receptor/0.447
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.447
3zk5Z18Cytochrome P450 monooxygenase PikC/0.447
4ia2BIVVitamin D3 receptor A/0.447
4enhFVXCholesterol 24-hydroxylase/0.446
2ntjP1HEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2ykcYKCHeat shock protein HSP 90-alpha/0.445
3dl9V2HVitamin D 25-hydroxylase/0.445
4b7sQLECytochrome P450 monooxygenase PikC/0.445
4jazSTLPeroxisome proliferator-activated receptor gamma/0.445
1rf9DBRCamphor 5-monooxygenase1.14.15.10.444
3tk3CPZCytochrome P450 2B41.14.14.10.444
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.443
3p6oETGCamphor 5-monooxygenase1.14.15.10.443
3zkyWT4Isopenicillin N synthase1.21.3.10.443
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.443
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.443
4ruoBIVVitamin D3 receptor A/0.443
3w0aDS5Vitamin D3 receptor/0.442
4ktl1CQCytochrome P450/0.442
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.441
3zkpERBErythromycin C-12 hydroxylase1.14.13.1540.441
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
3jynNDPQuinone oxidoreductase/0.440
4l9q9TPSerum albumin/0.440
4ly91YYGlucokinase regulatory protein/0.440