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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.600
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.600
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.594
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.584
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.581
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.581
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.579
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.577
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.577
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.575
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.574
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.573
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.569
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.566
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.564
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.558
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.557
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.557
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.556
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.553
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.551
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.549
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.549
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.536
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.533
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.531
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.528
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.527
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.526
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.522
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.519
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.516
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.513
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.502
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
1jbpADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.493
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.493
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.488
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.488
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.482
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.482
4yxsEMUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
4iayADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.478
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
2uvzGVJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
4xw4ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.472
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
4iazADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
4iakADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
4gv10XZRAC-alpha serine/threonine-protein kinase2.7.11.10.466
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
3idbANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.449
4fv6E57Mitogen-activated protein kinase 12.7.11.240.445
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440