Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3o8gO8GHTH-type transcriptional regulator EthR

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3o8gO8GHTH-type transcriptional regulator EthR/1.000
3q0uLL3HTH-type transcriptional regulator EthR/0.726
3tp0FO5HTH-type transcriptional regulator EthR/0.647
3q0vLL4HTH-type transcriptional regulator EthR/0.641
3o8hO8HHTH-type transcriptional regulator EthR/0.639
3sfi3SFHTH-type transcriptional regulator EthR/0.631
3g1mRF3HTH-type transcriptional regulator EthR/0.624
4dw60MNHTH-type transcriptional regulator EthR/0.537
3g1oRF1HTH-type transcriptional regulator EthR/0.491
3g1lRF2HTH-type transcriptional regulator EthR/0.490
4at0FADPossible succinate dehydrogenase/0.467
1kkq471Peroxisome proliferator-activated receptor alpha/0.462
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.460
2ykbYKBHeat shock protein HSP 90-alpha/0.456
3tdaPN0Cytochrome P450 2D6/0.455
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
1hb3SCVIsopenicillin N synthase1.21.3.10.450
5dcyNAPIridoid synthase1.3.1.990.449
2q9fC3SCholesterol 24-hydroxylase/0.448
3p6oETGCamphor 5-monooxygenase1.14.15.10.448
2ebaFADPutative glutaryl-CoA dehydrogenase/0.447
2ntvP1HEnoyl-[acyl-carrier-protein] reductase [NADH]/0.445
3cz7ACOHistone acetyltransferase RTT1092.3.1.480.444
3hdyFDAUDP-galactopyranose mutase/0.444
1ma0NADAlcohol dehydrogenase class-31.1.1.10.443
2ykiYKIHeat shock protein HSP 90-alpha/0.443
3mnrSD1Heat shock protein HSP 90-alpha/0.443
4blcNDPCatalase1.11.1.60.443
2iviACWIsopenicillin N synthase1.21.3.10.441
1bk0ACVIsopenicillin N synthase1.21.3.10.440