scPDB - Distribution of Binding site Similarity values of 3mb9 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3mb9	ZST	Aldose reductase	1.1.1.21

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
3mb9	ZST	Aldose reductase	1.1.1.21	1.000
3len	ZST	Aldose reductase	1.1.1.21	0.656
2dv0	ZST	Aldose reductase	1.1.1.21	0.645
2hv5	ZST	Aldose reductase	1.1.1.21	0.641
3m0i	ZST	Aldose reductase	1.1.1.21	0.640
2fz8	ZST	Aldose reductase	1.1.1.21	0.635
2fz9	ZST	Aldose reductase	1.1.1.21	0.632
1pwl	BFI	Aldose reductase	1.1.1.21	0.626
1z3n	3NA	Aldose reductase	1.1.1.21	0.624
2hvn	ZST	Aldose reductase	1.1.1.21	0.613
1iei	ZES	Aldose reductase	1.1.1.21	0.611
2pdx	ZST	Aldose reductase	1.1.1.21	0.610
3m4h	388	Aldose reductase	1.1.1.21	0.610
3lbo	LDT	Aldose reductase	1.1.1.21	0.608
2pdn	47D	Aldose reductase	1.1.1.21	0.607
3lql	LDT	Aldose reductase	1.1.1.21	0.607
2pd5	ZST	Aldose reductase	1.1.1.21	0.605
3mc5	393	Aldose reductase	1.1.1.21	0.605
2i16	LDT	Aldose reductase	1.1.1.21	0.603
2hvo	ZST	Aldose reductase	1.1.1.21	0.602
1t40	ID5	Aldose reductase	1.1.1.21	0.600
2pdb	ZST	Aldose reductase	1.1.1.21	0.596
2dux	ZST	Aldose reductase	1.1.1.21	0.591
2pdh	47D	Aldose reductase	1.1.1.21	0.589
4gca	2X9	Aldose reductase	1.1.1.21	0.589
2pdg	47D	Aldose reductase	1.1.1.21	0.588
2pdm	ZST	Aldose reductase	1.1.1.21	0.588
2pdc	393	Aldose reductase	1.1.1.21	0.585
3ght	LDT	Aldose reductase	1.1.1.21	0.584
2ikj	393	Aldose reductase	1.1.1.21	0.583
3ghs	LDT	Aldose reductase	1.1.1.21	0.583
1z89	62P	Aldose reductase	1.1.1.21	0.581
3ghu	LDT	Aldose reductase	1.1.1.21	0.579
2pdp	393	Aldose reductase	1.1.1.21	0.578
3m64	393	Aldose reductase	1.1.1.21	0.578
3ghr	LDT	Aldose reductase	1.1.1.21	0.577
1frb	ZST	Aldose reductase-related protein 2	/	0.576
2iki	388	Aldose reductase	1.1.1.21	0.575
3ld5	LDT	Aldose reductase	1.1.1.21	0.574
2i17	LDT	Aldose reductase	1.1.1.21	0.573
3g5e	Q74	Aldose reductase	1.1.1.21	0.571
4yu1	53N	Aldose reductase	1.1.1.21	0.570
2qxw	LDT	Aldose reductase	1.1.1.21	0.569
2pzn	393	Aldose reductase	1.1.1.21	0.568
1us0	LDT	Aldose reductase	1.1.1.21	0.567
2pdi	ZST	Aldose reductase	1.1.1.21	0.560
1t41	ID5	Aldose reductase	1.1.1.21	0.558
3t42	3T4	Aldose reductase	1.1.1.21	0.552
2duz	ZST	Aldose reductase	1.1.1.21	0.550
2pdj	393	Aldose reductase	1.1.1.21	0.548
3lz5	LDT	Aldose reductase	1.1.1.21	0.547
2pdl	TOL	Aldose reductase	1.1.1.21	0.515
2pdf	ZST	Aldose reductase	1.1.1.21	0.513
2pdu	393	Aldose reductase	1.1.1.21	0.513
2ikh	LIT	Aldose reductase	1.1.1.21	0.507
2fzd	TOL	Aldose reductase	1.1.1.21	0.494
1ah3	TOL	Aldose reductase	1.1.1.21	0.490
1zua	TOL	Aldo-keto reductase family 1 member B10	1.1.1	0.489
2pdq	47D	Aldose reductase	1.1.1.21	0.485
3g49	3G4	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.476
2xup	TZ5	Acetylcholinesterase	3.1.1.7	0.475
2nvc	ITA	Aldose reductase	1.1.1.21	0.468
2psj	CEI	Renilla-luciferin 2-monooxygenase	1.13.12.5	0.466
4ey7	E20	Acetylcholinesterase	3.1.1.7	0.466
4jt8	1NR	NAD-dependent protein deacetylase sirtuin-3, mitochondrial	3.5.1	0.464
2xui	TZ5	Acetylcholinesterase	3.1.1.7	0.462
2aov	C2M	Histamine N-methyltransferase	2.1.1.8	0.461
2inz	OHP	Aldose reductase	1.1.1.21	0.460
3f3y	4OA	Bile salt sulfotransferase	2.8.2.14	0.457
5cto	NTD	4-hydroxyphenylpyruvate dioxygenase	1.13.11.27	0.456
2pdy	FID	Aldose reductase	1.1.1.21	0.453
4jt9	1NS	NAD-dependent protein deacetylase sirtuin-3, mitochondrial	3.5.1	0.452
2xuq	TZ4	Acetylcholinesterase	3.1.1.7	0.451
4jsr	1NQ	NAD-dependent protein deacetylase sirtuin-3, mitochondrial	3.5.1	0.450
1pj6	FOL	Dimethylglycine oxidase	1.5.3.10	0.449
2f38	15M	Aldo-keto reductase family 1 member C3	/	0.449
2v0m	KLN	Cytochrome P450 3A4	/	0.449
2xuj	TZ5	Acetylcholinesterase	3.1.1.7	0.449
3u2c	SUZ	Aldose reductase	1.1.1.21	0.449
2agt	FID	Aldose reductase	1.1.1.21	0.448
2xuh	TZ4	Acetylcholinesterase	3.1.1.7	0.448
2xuo	TZ4	Acetylcholinesterase	3.1.1.7	0.448
3g4k	ROL	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.448
4x3u	SVR	Chromobox protein homolog 7	/	0.448
3jsx	CC2	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.447
5liu	388	Aldo-keto reductase family 1 member B10	1.1.1	0.447
1u65	CP0	Acetylcholinesterase	3.1.1.7	0.446
4ga8	SBI	Aldo-keto reductase family 1 member B10	1.1.1	0.446
2xuf	TZ4	Acetylcholinesterase	3.1.1.7	0.445
4bvn	P32	Beta-1 adrenergic receptor	/	0.445
4hcy	0YN	Transketolase	/	0.444
1oyn	ROL	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.443
3g4g	D71	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.443
3g72	A6T	Renin	3.4.23.15	0.443
4l5b	1UX	Deoxycytidine kinase	2.7.1.74	0.443
4lxj	LAN	Lanosterol 14-alpha demethylase	1.14.13.70	0.443
1uho	VDN	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.442
4m0f	1YK	Acetylcholinesterase	3.1.1.7	0.442
1el3	I84	Aldose reductase	1.1.1.21	0.441
2aou	CQA	Histamine N-methyltransferase	2.1.1.8	0.441
3g70	A5T	Renin	3.4.23.15	0.441
4kmz	FOL	Folate receptor beta	/	0.440