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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.615
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.591
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.541
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.535
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.532
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.519
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.507
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.505
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.504
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.502
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.496
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.491
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.487
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.478
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.473
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.463
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.462
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.456
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.456
4c36ZO9cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
2jedLG8Protein kinase C theta type2.7.11.130.451
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.451
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.450
4dymIYZActivin receptor type-12.7.11.300.449
1obnASVIsopenicillin N synthase1.21.3.10.448
1hb3SCVIsopenicillin N synthase1.21.3.10.446
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.446
2uvyGVIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2y60M8FIsopenicillin N synthase1.21.3.10.445
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.442
1hb1OCVIsopenicillin N synthase1.21.3.10.440
3cic316Beta-secretase 13.4.23.460.440
4othDRNSerine/threonine-protein kinase N1/0.440