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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3f108HG8-oxoguanine-DNA-glycosylase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3f108HG8-oxoguanine-DNA-glycosylase/1.000
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.461
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
2zsbADPPantothenate kinase2.7.1.330.459
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
2iyfERYOleandomycin glycosyltransferase2.4.10.456
3qfrFMNNADPH--cytochrome P450 reductase/0.456
3wagTYDGlycosyltransferase/0.456
1nj6A5AProline--tRNA ligase/0.454
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.453
2nr4FMNConserved protein/0.453
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.451
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.451
4driRAPSerine/threonine-protein kinase mTOR2.7.11.10.451
4driRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.451
1nj5P5AProline--tRNA ligase/0.450
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.449
4bfsZVSPantothenate kinase2.7.1.330.449
3gn73GNPoly [ADP-ribose] polymerase 12.4.2.300.448
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
3ensENSCoagulation factor X3.4.21.60.447
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.446
4y0kNAPAntE/0.446
1zapA70Candidapepsin-23.4.23.240.445
2fapRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.445
2fapRADSerine/threonine-protein kinase mTOR2.7.11.10.445
3br3ETHTH-type transcriptional regulator QacR/0.445
4drhRAPSerine/threonine-protein kinase mTOR2.7.11.10.445
4drhRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.445
1ja0FMNNADPH--cytochrome P450 reductase/0.444
4mvcCDCCholine-phosphate cytidylyltransferase A/0.444
2bn4FMNNADPH--cytochrome P450 reductase/0.443
2zsaADPPantothenate kinase2.7.1.330.443
4c0bATPmRNA cleavage and polyadenylation factor CLP1/0.443
4djhJDCKappa-type opioid receptor/0.443
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.442
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.442
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3hl0NADMaleylacetate reductase/0.442
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.442
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
1nsgRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.441
1nsgRADSerine/threonine-protein kinase mTOR2.7.11.10.441
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440