Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3eksCY9Actin-5C

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3eksCY9Actin-5C/1.000
3ekuCY9Actin-5C/0.676
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.471
4g3jVNTLanosterol 14-alpha-demethylase/0.471
1w6hTITPlasmepsin-23.4.23.390.468
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.465
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.464
4bb3KKAIsopenicillin N synthase1.21.3.10.463
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.461
3gw9VNILanosterol 14-alpha-demethylase/0.461
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.461
1bil0IURenin3.4.23.150.459
1rneC60Renin3.4.23.150.459
4isk1JYThymidylate synthase/0.459
1yb5NAPQuinone oxidoreductase1.6.5.50.458
1bim0QBRenin3.4.23.150.457
3gqvNAPEnoyl reductase LovC10.457
3pm9FADPutative oxidoreductase/0.457
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.456
3d91REMRenin3.4.23.150.455
1xe55FEPlasmepsin-23.4.23.390.454
1xs7MMIBeta-secretase 13.4.23.460.454
3cid318Beta-secretase 13.4.23.460.453
4x28FDAAcyl-CoA dehydrogenase FadE26/0.452
4x28FDAAcyl-CoA dehydrogenase FadE27/0.452
2ozuACOHistone acetyltransferase KAT6A/0.450
3ohh3HHBeta-secretase 13.4.23.460.450
4jtqNAPAldo-keto reductase family 1 member C2/0.450
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.449
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
2ejvNADL-threonine 3-dehydrogenase/0.448
2rcyNAPPyrroline-5-carboxylate reductase/0.448
3lpkZ76Beta-secretase 13.4.23.460.448
4lxk1YTBeta-secretase 13.4.23.460.447
1fm4DXCMajor pollen allergen Bet v 1-L/0.446
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.446
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.446
5dozNDPJamJ/0.446
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.445
3qwbNDPProbable quinone oxidoreductase1.6.5.50.445
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.445
4d89BXDBeta-secretase 13.4.23.460.445
5jlaNADPutative short-chain dehydrogenase/reductase/0.445
3lpjZ75Beta-secretase 13.4.23.460.444
3lqfNADGalactitol dehydrogenase/0.444
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.444
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.443
2rirNAPDipicolinate synthase subunit A/0.443
3gfbNADL-threonine 3-dehydrogenase/0.442
3k5dXLIBeta-secretase 13.4.23.460.442
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.442
4bfvZVVPantothenate kinase2.7.1.330.442
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.442
5dcyNAPIridoid synthase1.3.1.990.442
1e3sNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.441
2ahrNAPPyrroline-5-carboxylate reductase/0.441
4u8oFDAUDP-galactopyranose mutase/0.441
2c12FADNitroalkane oxidase1.7.3.10.440
2zb3NDPProstaglandin reductase 21.3.1.480.440
4oztP1AEcdysone receptor, putative/0.440
4q71FADBifunctional protein PutA/0.440