scPDB - Distribution of Binding site Similarity values of 3au8 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3au8	NDP	1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic	1.1.1.267

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
3au8	NDP	1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic	1.1.1.267	1.000
1jvs	NDP	1-deoxy-D-xylulose 5-phosphate reductoisomerase	1.1.1.267	0.495
3a14	NDP	1-deoxy-D-xylulose 5-phosphate reductoisomerase	/	0.482
4xj4	3AT	Cyclic GMP-AMP synthase	/	0.466
3inm	NDP	Isocitrate dehydrogenase [NADP] cytoplasmic	1.1.1.42	0.465
3anm	NDP	1-deoxy-D-xylulose 5-phosphate reductoisomerase	1.1.1.267	0.462
2hdh	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.459
2jcv	NDP	1-deoxy-D-xylulose 5-phosphate reductoisomerase	/	0.457
3anl	NDP	1-deoxy-D-xylulose 5-phosphate reductoisomerase	1.1.1.267	0.451
4anx	534	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.448
3ras	NDP	1-deoxy-D-xylulose 5-phosphate reductoisomerase	/	0.447
3gob	HXX	DdmC	/	0.445
4ewn	0VR	Imidazole glycerol phosphate synthase subunit HisF	4.1.3	0.445
3c0i	3AM	Peripheral plasma membrane protein CASK	2.7.11.1	0.444
1zmd	NAI	Dihydrolipoyl dehydrogenase, mitochondrial	1.8.1.4	0.443
2c3q	GTX	Glutathione S-transferase theta-1	2.5.1.18	0.441
3eml	ZMA	Adenosine receptor A2a	/	0.441
4r21	STR	Cytochrome P450 family 17 polypeptide 2	/	0.440