sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3a78 | 3EV | Vitamin D3 receptor |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3a78 | 3EV | Vitamin D3 receptor | / | 1.000 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.772 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.766 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.723 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.694 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.689 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.685 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.682 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.671 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.665 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.664 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.663 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.663 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.660 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.660 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.659 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.657 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.653 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.653 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.653 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.650 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.648 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.647 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.643 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.642 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.639 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.637 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.635 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.635 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.635 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.634 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.634 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.634 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.634 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.633 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.631 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.631 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.631 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.631 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.629 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.629 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.628 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.627 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.624 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.623 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.621 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.621 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.621 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.620 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.620 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.619 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.619 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.618 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.615 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.615 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.611 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.610 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.610 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.609 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.609 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.602 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.593 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.589 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.579 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.577 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.573 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.572 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.555 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.533 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.518 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.460 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.457 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.452 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.448 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.447 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.447 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.447 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.446 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 4l9q | 9TP | Serum albumin | / | 0.444 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.443 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 1osv | CHC | Bile acid receptor | / | 0.441 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.440 |