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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2qo7ANPEphrin type-A receptor 32.7.10.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2qo7ANPEphrin type-A receptor 32.7.10.11.000
2henADPEphrin type-B receptor 22.7.10.10.621
2qoqANPEphrin type-A receptor 32.7.10.10.603
2qo9ANPEphrin type-A receptor 32.7.10.10.553
2qocANPEphrin type-A receptor 32.7.10.10.522
4g2fC07Ephrin type-A receptor 32.7.10.10.478
4c3pACPAurora kinase A2.7.11.10.474
4gk3L87Ephrin type-A receptor 32.7.10.10.472
1mqbANPEphrin type-A receptor 22.7.10.10.470
2j0lANPFocal adhesion kinase 12.7.10.20.466
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.455
1bygSTUTyrosine-protein kinase CSK/0.448
4qnyANPMitogen activated protein kinase, putative/0.447
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.444
4gk4L90Ephrin type-A receptor 32.7.10.10.443
4qmlANPSerine/threonine-protein kinase 242.7.11.10.443
1jpaANPEphrin type-B receptor 22.7.10.10.442
2ijmATPFocal adhesion kinase 12.7.10.20.442
1i44ACPInsulin receptor2.7.10.10.440