Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2nmvADPUvrABC system protein B

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2nmvADPUvrABC system protein B/1.000
2d7dADPUvrABC system protein B/0.672
1lolXMPOrotidine 5'-phosphate decarboxylase4.1.1.230.479
3hv4L51Mitogen-activated protein kinase 14/0.469
3nnuEDBMitogen-activated protein kinase 14/0.466
4nt03DUOrotidine 5'-phosphate decarboxylase4.1.1.230.465
3e9hKAALysine--tRNA ligase6.1.1.60.462
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
2bxiAZQSerum albumin/0.458
2ghmLICMitogen-activated protein kinase 14/0.457
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.456
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
3bu5ATPInsulin receptor2.7.10.10.455
4lnkADPGlutamine synthetase6.3.1.20.455
3uwqU5POrotidine 5'-phosphate decarboxylase/0.454
1mgoNADAlcohol dehydrogenase E chain1.1.1.10.452
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.452
3sptUD1Bifunctional protein GlmU/0.452
4mb2ATPUncharacterized protein/0.452
4s32ANPMitogen-activated protein kinase 12.7.11.240.452
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.451
1ii6ADPKinesin-like protein KIF11/0.449
2yx1SFGtRNA (guanine(37)-N1)-methyltransferase Trm5b2.1.1.2280.449
2bw7ECSAdenylate cyclase/0.448
1j39UPGDNA beta-glucosyltransferase/0.447
1a71NADAlcohol dehydrogenase E chain1.1.1.10.446
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.446
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
1ir3ANPInsulin receptor2.7.10.10.445
2cmkCDPCytidylate kinase2.7.4.250.445
5cdgNAJAlcohol dehydrogenase E chain1.1.1.10.445
2yyuC5POrotidine 5'-phosphate decarboxylase/0.444
5ayzNCNNicotinate-nucleotide pyrophosphorylase [carboxylating]2.4.2.190.444
3d83GK6Mitogen-activated protein kinase 14/0.443
2py7ATPPhosphoenolpyruvate carboxykinase (ATP)/0.442
5kj6NAJAlcohol dehydrogenase E chain1.1.1.10.442
3nnwEDDMitogen-activated protein kinase 14/0.440
4wq5ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.440