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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.580
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.575
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.552
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.549
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.540
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.540
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.532
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.530
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.524
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.522
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.521
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.520
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.513
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.510
2uvyGVIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.496
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.491
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.482
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.478
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.472
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
3l0lHC3Nuclear receptor ROR-gamma/0.454
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.453
1xuoLA1Integrin alpha-L/0.452
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2uvzGVJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
3g7jGTXGlutathione transferase GST1-4/0.446
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.445
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.445
4hge15VTyrosine-protein kinase JAK2/0.444
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2y60M8FIsopenicillin N synthase1.21.3.10.442
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
3w78CBDFMN-dependent NADH-azoreductase/0.440