Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2gvdFKPAdenylate cyclase type 2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2gvdFKPAdenylate cyclase type 2/1.000
2gvdFKPAdenylate cyclase type 5/1.000
1cjkFOKAdenylate cyclase type 2/0.629
1cjkFOKAdenylate cyclase type 5/0.629
1cs4FOKAdenylate cyclase type 2/0.615
1cs4FOKAdenylate cyclase type 5/0.615
1cjtFOKAdenylate cyclase type 2/0.609
1cjtFOKAdenylate cyclase type 5/0.609
1culFOKAdenylate cyclase type 2/0.595
1culFOKAdenylate cyclase type 5/0.595
1tl7FOKAdenylate cyclase type 2/0.577
1tl7FOKAdenylate cyclase type 5/0.577
1cjuFOKAdenylate cyclase type 2/0.556
1cjuFOKAdenylate cyclase type 5/0.556
3maaFKPAdenylate cyclase type 2/0.553
3maaFKPAdenylate cyclase type 5/0.553
3c16FOKAdenylate cyclase type 2/0.543
3c16FOKAdenylate cyclase type 5/0.543
1u0hFOKAdenylate cyclase type 2/0.540
1u0hFOKAdenylate cyclase type 5/0.540
3c15FOKAdenylate cyclase type 2/0.528
3c15FOKAdenylate cyclase type 5/0.528
1cjvFOKAdenylate cyclase type 2/0.525
1cjvFOKAdenylate cyclase type 5/0.525
3c14FOKAdenylate cyclase type 2/0.509
3c14FOKAdenylate cyclase type 5/0.509