sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2g1n | 1IG | Renin | 3.4.23.15 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2g1n | 1IG | Renin | 3.4.23.15 | 1.000 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.716 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.657 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.651 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.637 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.635 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.628 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.623 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.622 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.619 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.614 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.605 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.592 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.587 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.581 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.581 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.574 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.569 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.569 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.569 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.567 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.558 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.547 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.543 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.534 | |
| 3vuc | HHE | Renin | 3.4.23.15 | 0.529 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.518 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.508 | |
| 3g6z | A7T | Renin | 3.4.23.15 | 0.507 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.507 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.497 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.495 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.489 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.488 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.480 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.468 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.466 | |
| 2g27 | 4LG | Renin | 3.4.23.15 | 0.461 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.459 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.453 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.447 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.447 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.447 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.447 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.444 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.444 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.443 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.443 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.440 |