sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2fj1 | CTC | Tetracycline repressor protein class D |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 1.000 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.629 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.616 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.606 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.595 | |
| 4aux | XTC | Tetracycline repressor protein class D | / | 0.590 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.585 | |
| 2xrl | DXT | Tetracycline repressor protein class D | / | 0.577 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.573 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.566 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.566 | |
| 2xb5 | I7T | Tetracycline repressor protein class D | / | 0.565 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.559 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.557 | |
| 5fkl | TDC | Tetracycline repressor protein class D | / | 0.549 | |
| 4d7m | TDC | Tetracycline repressor protein class D | / | 0.544 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.539 | |
| 5fkm | TDC | Tetracycline repressor protein class D | / | 0.532 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.529 | |
| 4abz | T1C | Tetracycline repressor protein class D | / | 0.513 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.512 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.510 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.486 | |
| 5fko | TDC | Tetracycline repressor protein class D | / | 0.468 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.466 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.461 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.460 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.458 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.456 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.453 | |
| 5fkn | TDC | Tetracycline repressor protein class D | / | 0.452 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.451 | |
| 4yxm | 2BA | DNA integrity scanning protein DisA | / | 0.446 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.444 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.444 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.443 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.443 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.440 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.440 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.440 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.440 |