sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2fhl | BNI | Avidin-related protein 4/5 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2fhl | BNI | Avidin-related protein 4/5 | / | 1.000 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.589 | |
| 2uyw | BTN | Avd protein | / | 0.572 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.530 | |
| 1y52 | BTN | Avidin-related protein 4/5 | / | 0.513 | |
| 1avd | BTN | Avidin | / | 0.503 | |
| 2avi | BTN | Avidin | / | 0.500 | |
| 4bx7 | B4F | Streptavidin | / | 0.485 | |
| 2uz2 | BTN | Avd protein | / | 0.482 | |
| 2c4i | BTN | Avidin | / | 0.469 | |
| 2rtf | BTN | Streptavidin | / | 0.466 | |
| 2izh | BTN | Streptavidin | / | 0.465 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.464 | |
| 4gda | BTN | Streptavidin | / | 0.464 | |
| 1mk5 | BTN | Streptavidin | / | 0.461 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.461 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.461 | |
| 1sri | DMB | Streptavidin | / | 0.459 | |
| 2izf | BTN | Streptavidin | / | 0.456 | |
| 1srf | MTB | Streptavidin | / | 0.455 | |
| 3vhi | VHI | Avidin | / | 0.455 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.453 | |
| 1rxh | BNI | Streptavidin | / | 0.452 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.452 | |
| 3up0 | D7S | aceDAF-12 | / | 0.452 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.451 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.450 | |
| 2rte | BTN | Streptavidin | / | 0.450 | |
| 4mo2 | FDA | UDP-galactopyranose mutase | / | 0.450 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.449 | |
| 4wso | NAD | Probable nicotinate-nucleotide adenylyltransferase | / | 0.449 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.449 | |
| 4dne | DTB | Streptavidin | / | 0.448 | |
| 1sre | HAB | Streptavidin | / | 0.447 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.446 | |
| 4hdg | GTP | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 1srg | MHB | Streptavidin | / | 0.445 | |
| 2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.445 | |
| 4z28 | BTN | Hoefavidin | / | 0.445 | |
| 2izl | IMI | Streptavidin | / | 0.444 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.443 | |
| 2rtg | BTN | Streptavidin | / | 0.443 | |
| 2rto | IMI | Streptavidin | / | 0.443 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.443 | |
| 3mzh | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.442 | |
| 1stp | BTN | Streptavidin | / | 0.441 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.441 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.441 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.441 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.440 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.440 | |
| 3wle | NAD | (R)-specific carbonyl reductase | / | 0.440 |