Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2ea2F77Methionine aminopeptidase 2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2ea2F77Methionine aminopeptidase 2/1.000
1yw8A75Methionine aminopeptidase 2/0.700
1yw9A84Methionine aminopeptidase 2/0.693
2ea4F79Methionine aminopeptidase 2/0.633
1r58AO5Methionine aminopeptidase 2/0.612
1yw7A41Methionine aminopeptidase 2/0.573
1r5gAO1Methionine aminopeptidase 2/0.562
2oazI96Methionine aminopeptidase 2/0.554
2ga2A19Methionine aminopeptidase 2/0.537
1qzyTDEMethionine aminopeptidase 2/0.533
1r5hAO2Methionine aminopeptidase 2/0.519
3aezGDPPantothenate kinase2.7.1.330.476
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.465
3h3t16HCollagen type IV alpha-3-binding protein/0.457
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
1xddAAYIntegrin alpha-L/0.450
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
2xlrFADPutative flavin-containing monooxygenase/0.448
4gd40WSLysine-specific demethylase 4A1.14.110.447
3h3qH13Collagen type IV alpha-3-binding protein/0.444
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.442
4bfvZVVPantothenate kinase2.7.1.330.442
1psa0ZLPepsin A3.4.23.10.440