sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2e40 | LGC | Beta-glucosidase 1A | 3.2.1.21 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2e40 | LGC | Beta-glucosidase 1A | 3.2.1.21 | 1.000 | |
| 2vrj | NCW | Beta-glucosidase A | 3.2.1.21 | 0.578 | |
| 3ptq | NFG | Beta-glucosidase 12 | / | 0.569 | |
| 2j7c | IDE | Beta-glucosidase A | 3.2.1.21 | 0.565 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.558 | |
| 2j7d | GI1 | Beta-glucosidase A | 3.2.1.21 | 0.542 | |
| 3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.535 | |
| 2wbg | LGS | Beta-glucosidase A | 3.2.1.21 | 0.530 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.514 | |
| 1e1f | PSG | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.507 | |
| 3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.491 | |
| 4mmd | 29E | Na(+):neurotransmitter symporter (Snf family) | / | 0.490 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.474 | |
| 4mmf | 29Q | Na(+):neurotransmitter symporter (Snf family) | / | 0.470 | |
| 1g1y | BCD | Neopullulanase 2 | / | 0.467 | |
| 4req | 5AD | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.467 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.466 | |
| 2xpk | Z0M | O-GlcNAcase NagJ | / | 0.463 | |
| 4mmc | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.463 | |
| 2y04 | 68H | Beta-1 adrenergic receptor | / | 0.462 | |
| 2jf6 | S55 | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.459 | |
| 2rd6 | 78P | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.459 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.459 | |
| 2oyl | IDC | Endoglycoceramidase II | / | 0.458 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.458 | |
| 4ug9 | 1EW | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.458 | |
| 3l3l | L3L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.457 | |
| 4lwa | Q13 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.456 | |
| 4r09 | URI | Toll-like receptor 8 | / | 0.456 | |
| 2oym | MNI | Endoglycoceramidase II | / | 0.455 | |
| 2rcw | AAI | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.455 | |
| 4r07 | URI | Toll-like receptor 8 | / | 0.455 | |
| 1uk0 | FRM | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.454 | |
| 1y5v | NE8 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.454 | |
| 4azh | LOG | Beta-N-acetylhexosaminidase | 3.2.1.52 | 0.453 | |
| 4mme | 29Q | Na(+):neurotransmitter symporter (Snf family) | / | 0.453 | |
| 3b4p | 3B4 | Phenazine biosynthesis protein A/B | / | 0.451 | |
| 3gn7 | 3GN | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.450 | |
| 1uk1 | FRQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.449 | |
| 4fr1 | 0V2 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.449 | |
| 4mm4 | 8PR | Na(+):neurotransmitter symporter (Snf family) | / | 0.449 | |
| 3anl | SYC | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.448 | |
| 2ycz | I32 | Beta-1 adrenergic receptor | / | 0.447 | |
| 3ny8 | JRZ | Beta-2 adrenergic receptor | / | 0.446 | |
| 4l6s | 1WQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.445 | |
| 3odu | ITD | C-X-C chemokine receptor type 4 | / | 0.443 | |
| 3oe9 | ITD | C-X-C chemokine receptor type 4 | / | 0.443 | |
| 4r5w | XAV | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.442 | |
| 2wb5 | VGB | O-GlcNAcase NagJ | / | 0.441 | |
| 3cui | X4S | Exoglucanase/xylanase | 3.2.1.91 | 0.441 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.440 | |
| 3ex8 | AIF | Riboflavin biosynthesis protein RibD | 1.1.1.193 | 0.440 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.440 |