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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2bxaC1FSerum albumin

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2bxaC1FSerum albumin/1.000
2ydfIO3Serum albumin/0.645
1hk2T44Serum albumin/0.607
1hk1T44Serum albumin/0.578
2bx8AZQSerum albumin/0.575
3lu7IPXSerum albumin/0.564
2bxiAZQSerum albumin/0.551
1hk3T44Serum albumin/0.538
3lu6IMXSerum albumin/0.527
2bxoOPBSerum albumin/0.525
2xvu9DNSerum albumin/0.519
4z69DIFSerum albumin/0.468
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.459
3tdvGDPGentamicin resistance protein/0.457
1obnASVIsopenicillin N synthase1.21.3.10.455
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.453
4l9zCOAL-malyl-CoA/beta-methylmalyl-CoA lyase4.1.3.240.453
2nliFMNLactate oxidase/0.449
4fl2ANPTyrosine-protein kinase SYK2.7.10.20.449
2vcmM11Isopenicillin N synthase1.21.3.10.448
3tdl11DSerum albumin/0.447
3vn9ANKDual specificity mitogen-activated protein kinase kinase 62.7.12.20.447
1crbRTLRetinol-binding protein 1/0.446
2eixFADNADH-cytochrome b5 reductase/0.445
4bn1ADPAurora kinase A2.7.11.10.445
3tdwGDPGentamicin resistance protein/0.444
2vwiANPSerine/threonine-protein kinase OSR12.7.11.10.443
3adaNADSubunit alpha of sarocosine oxidase/0.443
4l8u9AZSerum albumin/0.443
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.442
3lfbZ87Mitogen-activated protein kinase 14/0.442
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.442
4c4h7RODual specificity protein kinase TTK2.7.12.10.442
1r9oFLPCytochrome P450 2C9/0.441
1wlvCOAPhenylacetic acid degradation protein PaaI/0.441
2imkGTXAGAP009194-PA/0.441
3x2vATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
4lb2DM5Serum albumin/0.441
2cahNDPCatalase1.11.1.60.440
3ix9MTXDihydrofolate reductase1.5.1.30.440
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.440
4k2xFADPolyketide oxygenase/hydroxylase/0.440