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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2bf7HBIPteridine reductase 11.5.1.33

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2bf7HBIPteridine reductase 11.5.1.331.000
2bfpH4BPteridine reductase 11.5.1.330.699
1e92HBIPteridine reductase 11.5.1.330.677
3h4vDVPPteridine reductase 11.5.1.330.615
2bfaCB3Pteridine reductase 11.5.1.330.596
2qhxFE1Pteridine reductase 11.5.1.330.583
2bfmTOPPteridine reductase 11.5.1.330.552
1p33MTXPteridine reductase 11.5.1.330.498
1e7wMTXPteridine reductase 11.5.1.330.465
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.458
1mxfMTXPutative pteridine reductase 2/0.447