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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2abaSTRPentaerythritol tetranitrate reductase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2abaSTRPentaerythritol tetranitrate reductase/1.000
1h60STRPentaerythritol tetranitrate reductase/0.601
1h61PDNPentaerythritol tetranitrate reductase/0.568
1h62ANBPentaerythritol tetranitrate reductase/0.479
1bil0IURenin3.4.23.150.460
1obnASVIsopenicillin N synthase1.21.3.10.458
1hb3SCVIsopenicillin N synthase1.21.3.10.457
2g247IGRenin3.4.23.150.455
1gvrTNLPentaerythritol tetranitrate reductase/0.453
2jb4A14Isopenicillin N synthase1.21.3.10.453
2ikuLIYRenin3.4.23.150.451
1q84TZ4Acetylcholinesterase3.1.1.70.446
2g1s4IGRenin3.4.23.150.444
3kftNADPentaerythritol tetranitrate reductase/0.444
2vbpVB1Isopenicillin N synthase1.21.3.10.440