sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1z5w | GTP | Tubulin gamma-1 chain |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1z5w | GTP | Tubulin gamma-1 chain | / | 1.000 | |
| 1z5v | GSP | Tubulin gamma-1 chain | / | 0.717 | |
| 4wbn | GTP | Tubulin alpha-1B chain | / | 0.493 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.479 | |
| 4ihj | GTP | Tubulin alpha-1B chain | / | 0.477 | |
| 3cb2 | GDP | Tubulin gamma-1 chain | / | 0.469 | |
| 4o4l | GTP | Tubulin alpha-1B chain | / | 0.468 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.462 | |
| 4tv9 | GTP | Tubulin alpha-1B chain | / | 0.462 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.458 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.455 | |
| 2ym1 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.451 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 5dp2 | NAP | CurF | / | 0.449 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.448 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.447 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 2ylt | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.445 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.445 | |
| 3up5 | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.444 | |
| 3v2u | ATP | Protein GAL3 | / | 0.444 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.442 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.441 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.440 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.440 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.440 |