sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1v11 | TDP | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1v11 | TDP | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 1.000 | |
| 1d7y | FAD | Ferredoxin reductase | / | 0.469 | |
| 3dj4 | UD1 | Bifunctional protein GlmU | / | 0.465 | |
| 1q97 | ATP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.464 | |
| 2nom | DUT | Poly(A) polymerase, putative | / | 0.461 | |
| 1px2 | ATP | Synapsin-1 | / | 0.460 | |
| 5fko | TDC | Tetracycline repressor protein class D | / | 0.458 | |
| 2dpx | GDP | GTP-binding protein RAD | / | 0.457 | |
| 2wd4 | TBV | Ascorbate peroxidase | / | 0.457 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.457 | |
| 4y8v | ADP | Acyl-CoA synthetase (NDP forming) | / | 0.455 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.452 | |
| 1u28 | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.451 | |
| 1g4p | FQP | Thiamine-phosphate synthase | / | 0.450 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 3w8r | ACP | Uridine kinase | / | 0.450 | |
| 3pxv | FMN | Nitroreductase | / | 0.449 | |
| 2e0a | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.448 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.447 | |
| 1gjv | AGS | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.7.11.4 | 0.446 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 2wqe | ADP | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 3lu7 | IPX | Serum albumin | / | 0.446 | |
| 2bxi | AZQ | Serum albumin | / | 0.445 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2bry | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.443 | |
| 3ef6 | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.443 | |
| 3lgx | ATP | D-alanine--poly(phosphoribitol) ligase subunit 1 | / | 0.443 | |
| 1uof | PNN | Deacetoxycephalosporin C synthase | 1.14.20.1 | 0.442 | |
| 3hgm | ATP | TRAP-T-associated universal stress protein TeaD | / | 0.441 | |
| 4jld | ADP | Adenylate kinase | / | 0.441 | |
| 4z69 | DIF | Serum albumin | / | 0.441 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 |