Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1uy8PU5Heat shock protein HSP 90-alpha

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1uy8PU5Heat shock protein HSP 90-alpha/1.000
2ykjYKJHeat shock protein HSP 90-alpha/0.765
1uy6PU3Heat shock protein HSP 90-alpha/0.742
1uy9PU6Heat shock protein HSP 90-alpha/0.716
1uykPUXHeat shock protein HSP 90-alpha/0.708
2ykcYKCHeat shock protein HSP 90-alpha/0.701
2h55DZ8Heat shock protein HSP 90-alpha/0.693
3ft8MOJHeat shock protein HSP 90-alpha/0.683
1uydPU8Heat shock protein HSP 90-alpha/0.681
1uyhPU0Heat shock protein HSP 90-alpha/0.681
2fwzH71Heat shock protein HSP 90-alpha/0.681
1uy7PU4Heat shock protein HSP 90-alpha/0.668
3o0iP54Heat shock protein HSP 90-alpha/0.662
1uyfPU1Heat shock protein HSP 90-alpha/0.658
2ykeYKEHeat shock protein HSP 90-alpha/0.658
1uyiPUZHeat shock protein HSP 90-alpha/0.654
3inwJZBHeat shock protein HSP 90-alpha/0.649
1uyePU9Heat shock protein HSP 90-alpha/0.642
2qg2A91Heat shock protein HSP 90-alpha/0.641
2ykiYKIHeat shock protein HSP 90-alpha/0.631
1uycPU7Heat shock protein HSP 90-alpha/0.629
3hz5Z64Heat shock protein HSP 90-alpha/0.628
3inxJZCHeat shock protein HSP 90-alpha/0.623
1uymPU3Heat shock protein HSP 90-beta/0.621
3mnrSD1Heat shock protein HSP 90-alpha/0.613
2fwyH64Heat shock protein HSP 90-alpha/0.607
2wi72KLHeat shock protein HSP 90-alpha/0.605
3o6o94MHeat shock protein 83/0.601
4bqg50QHeat shock protein HSP 90-alpha/0.599
2yee2ECHeat shock protein HSP 90-alpha/0.591
3qdd94MHeat shock protein HSP 90-alpha/0.588
3d0bSNXHeat shock protein HSP 90-alpha/0.587
4nh82LCHeat shock protein HSP 90-alpha/0.585
4eftEFTHeat shock protein HSP 90-alpha/0.577
2wi4ZZ4Heat shock protein HSP 90-alpha/0.562
3hz137DHeat shock protein HSP 90-alpha/0.562
4efuEFUHeat shock protein HSP 90-alpha/0.562
2ykbYKBHeat shock protein HSP 90-alpha/0.557
4awo99BHeat shock protein HSP 90-alpha/0.552
2yeiXQIHeat shock protein HSP 90-alpha/0.536
2yk2YJWHeat shock protein HSP 90-alpha/0.523
3opdHIEHeat shock protein 83/0.522
4hy6FJ1Heat shock protein HSP 90-alpha/0.507
3q5kD1UHeat shock protein 83-1/0.506
4awp99AHeat shock protein HSP 90-alpha/0.503
2yjxYJXHeat shock protein HSP 90-alpha/0.491
4awq592Heat shock protein HSP 90-alpha/0.491
2xhrC0PHeat shock protein HSP 90-alpha/0.487
2yejZZ3Heat shock protein HSP 90-alpha/0.479
3ekrPY9Heat shock protein HSP 90-alpha/0.473
4z1fH71Heat shock protein 75 kDa, mitochondrial/0.469
3r4pFU7Heat shock protein HSP 90-alpha/0.467
3hhu819Heat shock protein HSP 90-alpha/0.461
2qg0A94Heat shock protein HSP 90-alpha/0.459
2bt0CT5Heat shock protein HSP 90-alpha/0.458
1zw9H64ATP-dependent molecular chaperone HSP82/0.457
4bqjXKLHeat shock protein HSP 90-alpha/0.456
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.451
3k974CDHeat shock protein HSP 90-alpha/0.447
4jqlVJ6Heat shock protein HSP 90-alpha/0.447
3rlr3RRHeat shock protein HSP 90-alpha/0.445
2wi6ZZ6Heat shock protein HSP 90-alpha/0.443
3rlq3RQHeat shock protein HSP 90-alpha/0.442
1yc14BCHeat shock protein HSP 90-alpha/0.441
4uyf73BBromodomain-containing protein 2/0.440